Kurt Lenz, Heide Hörtnagl, Dieter Magometschnigg, Gunter Kleinberger, Wilfred Druml, Anton Laggner – 1 September 1985 – To obtain further pathophysiological details concerning the development of cardiovascular disturbances in severe liver disease, the state of the autonomic nervous system, the function of the baroreceptor reflex pathway and the responsiveness of the cardiovascular system to noradrenaline, angiotensin II and isoprenaline were investigated in 11 patients with hepatic encephalopathy and in 10 healthy control subjects.

Jutta Lindenborn‐Fotinos, Harold Baum, Peter A. Berg – 1 September 1985 – Sera from patients with primary biliary cirrhosis reacted with four major bands in beef heart mitochondria and ATPase extract when analyzed by immunoblot after sodium dodecyl sulfate‐polyacrylamide gel electrophoresis. These four immunologically reactive bands corresponded to protein bands with molecular weights of about (a) 80,000; (b) 63,000; (c) 56,000; and (d) 43,000 to 46,000. An additional immunoreactive band was found with some high‐titered primary biliary cirrhosis sera at 36,000.

Esteban Celis, Ikunoshin Kato, Richard W. Miller, Tse Wen Chang – 1 September 1985 – The role of accessory cells (antigen‐presenting cells) in binding HBsAg in the response of human T cells to this antigen was studied. Antibodies to HBsAg of IgG class increased significantly the amount of HBsAg that was captured and internalized by accessory cells in vitro. On the other hand, antibodies to HBsAg of IgM class or the F(ab‐)2 and Fab fragments of antibodies to HBsAg of IgG class did not modify the amount of HBsAg associated to these cells.

Jean‐Claude Homberg, Nielsen Abuaf, Samir Helmy‐Khalil, Michel Biour, Raoul Poupon, Shamsul Islam, François Darnis, Victor Georges Levy, Pierre Opolon, Michel Beaugrand, Jacques Toulet, Gaby Danan, Jean‐Pierre Benhamou – 1 September 1985 – A study from five hepatology units documenting 157 cases of drug‐induced hepatitis and a second study from a laboratory of immunology which tested more than 100,000 sera permitted us to establish the frequency of antiorganelle antibodies and their diagnostic value in drug‐induced hepatitis.

Robert J. Fallon, Alan L. Schwartz – 1 September 1985

Masayasu Inoue – 1 September 1985

1 September 1985

1 September 1985

Mack C. Mitchell, James J. Potter, Esteban Mezey, Helmut K. Seitz, Siegrid Veith, Peter Czygan, Johann Bösche, Bernd Simon, Burkhard Simon, Roland Gugler – 1 September 1985

Catherine L. Troisi, F. Blaine Hollinger – 1 September 1985 – An IgM‐specific anti‐[anti‐HBs] antibody was detected by radioimmunoassay using anti‐IgM‐coated beads and 125I‐labeled anti‐HBs. This antiidiotype was found only in the sera of hepatitis B virus‐infected patients, both acute and chronic. However, not all HBsAg‐positive patients exhibited this reaction, and activity was correlated with the presence of HBeAg. Approximately 93% of sera that contained antiidiotype activity also contained HBeAg. Conversely, 70% of the sera positive for HBeAg reacted in the IgM assay.