Hepatology—the next five years
Steven Schenker – 1 January 1986
Branched chain amino acids in hepatic encephalopathy
Cerra Fb, Cheung Nk, Fischer Je, Harold O. Conn – 1 January 1986 – Seventy‐five patients with acute hepatic decompensation superimposed on chronic alcoholic cirrhosis were prospectively randomized for a blinded trial of the treatment of hepatic.
Digestive Disease Week
1 January 1986
Assessment of short‐term prognosis after variceal bleeding in patients with alcoholic cirrhosis by early measurement of portohepatic gradient
J. P. Vinel, J. Cassigneul, M. Levade, J. J. Voigt, J. P. Pascal – 1 January 1986 – Seventy‐two consecutively admitted patients with biopsy‐proven alcoholic cirrhosis and a bleeding episode endoscopically proven to originate from ruptured esophageal varices were studied. Hemodynamic assessment was performedwithin 48 hr of admission using the transjugular approach.
To the editor
Simon Gelman, Fumio Nomura, Hitoshi Hatano, Kunihiko Ohnishi, Kunio Okuda – 1 January 1986
Acute fatty liver of pregnancy: A clinicopathologic study of 35 cases
Donald B. Rolfes, Kamal G. Ishak – 1 November 1985 – Acute fatty liver of pregnancy is a disease of the third trimester which is generally considered to be rare and to have a grave prognosis. This study found an optimistic outlook for patients with acute fatty liver of pregnancy due to early termination of the pregnancy as well as the recognition of milder cases. In prospectively followed women, a maternal mortality of 8% and a fetal mortality of 14% were observed.
Halothane hepatitis without halothane: Role of inapparent circuit contamination and its prevention
Rajiv R. Varma, Robert C. Whitesell, Marwan M. Iskandarani – 1 November 1985 – Halothane and other halogenated anesthetic agents are liquids which are highly soluble in rubber and plastic materials widely used as components of anesthesia machines. These agents must be administered using machines equipped with vaporizers. We report a patient with a past history of halothane hepatitis in whom recurrence was suspected despite the fact that halothane had been avoided purposely during the subsequent operation.
Congenital portacaval shunt in rats: Liver adaptation to lack of portal vein—a light and electron microscopic study
Paulette Bioulac‐Sage, Jean Saric, Lilianne Boussarie, Charles Balabaud – 1 November 1985 – In five rats with congenital portacaval shunt, liver atrophy, hyperplastic foci in the periportal zone, atrophic hepatocytes in the centrolobular zone, well‐preserved hepatocyte ultrastructure with abundant rough endoplasmic reticulum, packed mitochondria and numerous peroxisomes were observed as in surgical portacaval shunt. However, portal triads were abnormal in contrast to surgical shunt. In large portal triads, hepatic arteries were prominent, bile ducts numerous and portal veins were lacking.
Halothane hepatitis sans halothane
Harold O. Conn, Jonas Skornicki – 1 November 1985
Histopathology of early and late human hepatic allograft rejection: Evidence of progressive destruction of interlobular bile ducts
John M. Vierling, Robert H. Fennell – 1 November 1985 – Cholestasis and injury of interlobular bile ducts occur during rejection of human hepatic allografts. However, knowledge of the nature and progression of bile duct injury during rejection remains incomplete. To define the role of inflammation in bile duct damage, we assessed the light microscopic appearance of hepatic tissue from selected patients in whom allograft failure was solely due to rejection. Nine patients with rejection were easily separated into two groups based on the duration of the allograft survival.