Hepatology elsewhere
Harold O. Conn – 1 January 1986
To the Editor
John Wahren, Roberto J. Groszmann, Jaime Bosch – 1 January 1986
A comparative study of the effects of insulin/glucagon infusions, parenteral amino acids and high dose corticosteroids on survival in a rabbit model of acute fulminant hepatitis
Gerald Y. Minuk.M.D., Thomas A. Sherman, Eldon A. Shaffer, Seamus K. Kelly – 1 January 1986 – Acute fulminant hepatitis was induced in 55 healthy adult male rabbits with the potent hepatotoxin galactosamine hydrochloride (3.75 mmoles per kg i.v.). Control rabbits (n = 27) were divided into three groups: Group I (n = 10) underwent sham surgery for placement of an indwelling central venous catheter; Group II (n = 9) received 5% dextrose and water via an indwelling central venous catheter, and Group III (n = 8) received daily intramuscular injections of 0.9% sodium chloride.
Substrates and products of purified rat liver bilirubin UDP ‐ glucuronosyltransferase
Namita Roy Chowdhury, Irwin M. Arias, Mitchell Lederstein, Jayanta Roy Chowdhury – 1 January 1986 – To determine whether the isoform of UDP‐glucuronosyltransferase which catalyzes the formation of bilirubin monoglucuronide also mediates the formation of bilirubin diglucuronide and other specific sugar conjugates of bilirubin, Wistar rats were treated with clofibrate (300 mg per kg i.p. × 7 days); this resulted in a 200% increase in hepatic transferase specific activity for bilirubin.
To the editor
Manuel Rodriguez, Ramon Perez, Pedro Sala, Luis Rodrigo, Leonard B. Seeff, Antonio Ponzetto, Jay H. Hoofnagle, John L. Gerin – 1 January 1986
To the Editor
V. Arroyo, A. Rimola, J. Felisart, J. Cabrera, William G. Rector – 1 January 1986
Short‐term effects of propranolol on portal venous pressure
Guadalupe Garcia‐Tsao, Norman D. Grace, Roberto J. Groszmann, Harold O. Conn, Max M. Bermann, Michael J. C. Patrick, Steven S. Morse, Jeanne L. Alberts – 1 January 1986 – The present study was designed to investigate the effect of propranolol on portal pressure of patients with alcoholic cirrhosis and portal hypertension and to correlate these effects with clinical and laboratory parameters. The mean baseline hepatic venous pressure gradient in the 50 patients studied was of 18.2 ± 4.1 mm Hg.
The usefulness of microscopic bile examination in patients with suspected microlithiasis: A prospective evaluation
Jean‐Charles Delchier, Paul Benfredj, Anne‐Marie Preaux, Jean‐Michel Metreau, Daniel Dhumeaux – 1 January 1986 – Gallbladder bile collected by duodenal intubation or during surgery was examined microscopically in patients who werefree of stones and in patients with proven stones. None of the 16 patients free of stones had cholesterol monohydrate crystals or calcium bilirubinate granules in bile.