Periductal fibrosis and lipocytes (fat‐storing cells or ito cells) during biliary atresia in the lamprey

Kazuhide Yamamoto, Patricia A. Sargent, Murray M. Fisher, John H. Youson – 1 January 1986 – Transmission and scanning electron microscopy were utilized to follow the degeneration of bile ducts of lampreys (Petromyzon marinus L.) during metamorphosis. The convoluted bile ducts of larval lampreys are surrounded by rich sinusoids, but this intimate biliovascular relationship is lost during metamorphosis because the bile duct degeneration is accompanied by the development of thick periductal fibrosis.

Assessment of short‐term prognosis after variceal bleeding in patients with alcoholic cirrhosis by early measurement of portohepatic gradient

J. P. Vinel, J. Cassigneul, M. Levade, J. J. Voigt, J. P. Pascal – 1 January 1986 – Seventy‐two consecutively admitted patients with biopsy‐proven alcoholic cirrhosis and a bleeding episode endoscopically proven to originate from ruptured esophageal varices were studied. Hemodynamic assessment was performedwithin 48 hr of admission using the transjugular approach.

Acute fatty liver of pregnancy: A clinicopathologic study of 35 cases

Donald B. Rolfes, Kamal G. Ishak – 1 November 1985 – Acute fatty liver of pregnancy is a disease of the third trimester which is generally considered to be rare and to have a grave prognosis. This study found an optimistic outlook for patients with acute fatty liver of pregnancy due to early termination of the pregnancy as well as the recognition of milder cases. In prospectively followed women, a maternal mortality of 8% and a fetal mortality of 14% were observed.

Halothane hepatitis without halothane: Role of inapparent circuit contamination and its prevention

Rajiv R. Varma, Robert C. Whitesell, Marwan M. Iskandarani – 1 November 1985 – Halothane and other halogenated anesthetic agents are liquids which are highly soluble in rubber and plastic materials widely used as components of anesthesia machines. These agents must be administered using machines equipped with vaporizers. We report a patient with a past history of halothane hepatitis in whom recurrence was suspected despite the fact that halothane had been avoided purposely during the subsequent operation.

Congenital portacaval shunt in rats: Liver adaptation to lack of portal vein—a light and electron microscopic study

Paulette Bioulac‐Sage, Jean Saric, Lilianne Boussarie, Charles Balabaud – 1 November 1985 – In five rats with congenital portacaval shunt, liver atrophy, hyperplastic foci in the periportal zone, atrophic hepatocytes in the centrolobular zone, well‐preserved hepatocyte ultrastructure with abundant rough endoplasmic reticulum, packed mitochondria and numerous peroxisomes were observed as in surgical portacaval shunt. However, portal triads were abnormal in contrast to surgical shunt. In large portal triads, hepatic arteries were prominent, bile ducts numerous and portal veins were lacking.

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