Intraoperative ultrasound in detecting hepatic metastases

Kenneth J. W. Taylor – 1 March 1988 – As a new screening procedure, intraoperative ultrasonography using high‐resolution real‐time instruments was used routinely in 84 colorectal cancer operations to scan the entire liver for liver metastases. In 10 operations (11.9%), intraoperative ultrasonography identified 14 previously unrecognized metastatic tumors, all of which were less than 2 cm in size and were nonpalpable.

Cytochrome p‐450 gene expression in the functional units of the fetal liver

Jose Chianale, Caroline Dvorak, Donna L. Farmer, Linda Michaels, Jorge J. Gumucio – 1 March 1988 – Hepatocytes of the right and left lobes of the fetal liver are surrounded by different microenvironments. The right and left lobes of the fetal liver are perfused by vascular systems carrying different concentrations of oxygen and constitute distinct functional units. The aim of this study was to assess the expression of the phenobarbital‐inducible cytochrome P‐450 b,e genes in hepatocytes of the right and left fetal liver lobes in mice.

An experimental transmission of woodchuck hepatitis virus to young chinese marmots

Jin Zhihong, Zhao Guolong, Xiong Shisong, Kou Pingyuan, Ma Lili, Chen Hongtao, Qi Jianying, Ba Qiuju, Mai Kai – 1 March 1988 – Fourteen young Chinese marmots (Marmota bobak sibirica Radde) were randomly allocated to two groups of seven each. They were injected intrahepatically with a standard woodchuck hepatitis virus challenge pool or a negative pool, prepared from sera of woodchucks with and without woodchuck hepatitis virus infection, respectively. Marmot No.

Cholesterol nucleation‐influencing activity in t‐tube bile

Albert K. Groen, Jan P. J. Stout, Jan A. G. Drapers, Frans J. Hoek, Rob Grijm, Guido N. J. Tytgat – 1 March 1988 – Nucleation‐influencing activity was determined in T‐tube bile samples derived from patients with obstructive jaundice. Since native T‐tube bile samples do not nucleate, nucleation‐influencing activity was determined by measuring the influence of T‐tube bile on the nucleation time of model bile.

Pathology of chronic hepatitis b virus infection in children: With special reference to the intrahepatic expression of hepatitis B virus antigens

Hey‐Chi Hsu, Yon‐Ho Lin, Mei‐Hwei Chang, Ih‐Jen Su, Ding‐Shinn Chen – 1 March 1988 – The clinical, virologic and pathologic features of chronic hepatitis B virus infection were studied in 66 children, of whom 29 were symptomatic and 37 asymptomatic. The majority (79%) of symptomatic children had histologically aggressive diseases: 11 had chronic active hepatitis and 10 had cirrhosis. In contrast, most asymptomatic children had nonaggressive diseases (35 cases); only 2 had chronic active hepatitis.

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