Ramjeet S. Pemsingh, Brian R. Macpherson, Gerald W. Scott – 1 November 1987 – This study identified mucus granules, determined mode of release and quantified their volume in the gallbladder epithelium of Richardson's ground squirrels (Spermophilus richardsonii) fed a lithogenic diet of 2% cholesterol to experimentally induce gallstone formation. Tissue was examined using light microscopy histochemistry, scanning and transmission electron microscopy, as well as autoradiography and morphometry at the electron microscopic level.

Paul Genecin – 1 November 1987

Henk F. J. Hendriks, Adriaan Brouwer, Dick L. Knook – 1 November 1987

Willis C. Maddrey – 1 November 1987

Harold O. Conn – 1 November 1987

Anne‐Marie Durand‐Schneider, Michèle Maurice, Micheline Dumont, Gérard Feldmann – 1 November 1987 – The hepatocyte plasma membrane presents a morphological and functional regionalization into three domains: the sinusoidal; the lateral, and the canalicular. The mechanisms responsible for the biogenesis and maintenance of this regionalization are poorly understood. In this work, we have used colchicine and phalloidin, two drugs known to interfere with the secretory processes in hepatocytes, to study whether they also affect the transport of membrane proteins.

C. L. Witzleben, Milton Finegold, David A. Piccoli, William R. Treem – 1 November 1987 – The diagnosis of arteriohepatic dysplasia may be difficult, particularly in very young patients with no family history, and the pathogenesis of the disorder remains obscure. It has been reported that the typical ultrastructural changes of cholestasis are scant in this condition and proposed that there is a failure of the hepatocytes to secrete bile into the canaliculi.

David L. Williams, Edward R. Sherwood, Rose B. McNamee, Ernest L. Jones, I. William Browder, Nicholas R. di Luzio – 1 November 1987 – Previous studies from our laboratory have demonstrated that particulate glucan is efficacious in the therapy of a syngeneic murine reticulum cell sarcoma (M5706), which specifically metastasizes from its primary site to the liver. The present study was undertaken to examine the therapeutic efficacy of a newly developed soluble glucan, in combination with cyclophosphamide in the treatment of hepatic metastatic disease.

Erik Christensen – 1 November 1987

Kay Tanaka – 1 November 1987 – Treatment of rats with hypoglycaemic doses of hypoglycin has been shown to abolish the relative detritiation of [2‐3H, U‐14C]glucose [Osmundsen, Billington, Taylor & Sherratt (1978) Biochem. J. 170, 337–342], indicating that both the Cori and the glucose/glucose 6‐phosphate cycles were inhibited in vivo. This inhibition was confirmed and, in addition, it was shown that the conversion in vivo of both [14C]lactate and [14C]fructose into glucose was decreased after hypoglycin treatment.