Increase in the number of fenestrae in mouse endothelial liver cells by altering the cytoskeleton with cytochalasin B
Anne‐Marie Steffan, Jean‐Louis Gendrault, André Kirn – 1 November 1987 – Endothelial cells of the hepatic sinusoid isolated from mice livers and maintained in culture display typical fenestrae grouped in sieve plates. Treatment with cytochalasin B led to no significant change in the mean diameter of the fenestrae but to an increase in their number and in the porosity of the cells (percentage of the cellular surface opened by the fenestrae) which attained up to 300% of that of the controls.