Program for the postgraduate course
1 September 1985
Acetaminophen hepatotoxicity and targeted rescue: A model for specific chemotherapy of hepatocellular carcinoma
George Y. Wu, Catherine H. Wu, Mark I. Rubin – 1 September 1985 – We have taken advantage of the presence of hepatic receptors for galactose‐terminal (asialo‐)glycoproteins to achieve targeted rescue of differentiated hepatocytes from acetaminophen‐induced toxicity in vitro. To accomplish this, a conjugate was formed by covalent coupling of N‐acetylcysteine (an acetaminophen antagonist) to galactose‐terminal (asialo‐)fetuin.
The liver and biliary system. Edited by P. W. Brunt, M. S. Losowsky and A. E. Read. London: William Heinemann Medical Books, Ltd., 1984.£7.95
Charles S. Davidson, Wade Volwiler – 1 September 1985
Diagnostic value of different antiliver/kidney microsome antibodies
M. Rizzetto, O. Crivelli, C. Andre, N. Abuaf, J. C. Homberg, Hyman J. Zimmerman – 1 September 1985
Polycythemia and the budd‐chiari syndrome: Study of serum erythropoietin and bone marrow erythroid progenitors
Victor Georges Levy, Agnès Ruskone, Claude Baillou, Diana Thierman‐Duffaud, Albert Najman, Georges Albert Boffa – 1 September 1985 – The mechanism of polycythemia associated with the Budd‐Chiari syndrome is unknown. Erythropoiesis in 10 patients with Budd‐Chiari syndrome was studied in an attempt to distinguish prior unrecognized polycythemia vera from secondary polycythemia.
Altered thiol and calcium homeostasis in oxidative hepatocellular injury
Giorgio Bellomo, Sten Orrenius – 1 September 1985
Induction by drugs of hepatitis and autoantibodies to cell organelles: Significance and interpretation
Ian R. Mackay – 1 September 1985
Hepatic Radiography. Edited by Michael E. Bernardino, M.D. and Peter J. Sones, Jr., M.D. 319 pp. + x. New York: Macmillan, 1984. $65.00
Stanley C. Foster, Stefan C. Schatzki – 1 September 1985
Time course and mechanism of alterations in proton relaxation during liver regeneration in the rat
H. Dirk Sostman, John C. Gore, M. Wayne Flye, G. Allan Johnson, Robert J. Herfkens – 1 July 1985 – We studied the proton T1 and T2, water and lipid content of regenerating rat liver from 1 to 7 days after 70% hepatectomy. Liver from normal and sham‐operated animals and splenic tissue from all animals were studied as controls. In vivo proton spectroscopy and imaging of liver was performed in a separate group of control and posthepatectomy rats. The T2 of regenerating liver, but not of sham or normal control liver, was prolonged.