Karl‐Joseph Paquet, Hubertus Feussner – 1 July 1985 – A prospective randomized controlled clinical trial was performed in 43 consecutive histologically proved cirrhotic patients with endoscopically proved actively bleeding esophageal varices. Twenty‐two were randomly selected to have esophageal tamponade with the Sengstaken‐Blakemore tube, and 21 were selected to have endoscopic sclerosis of the esophageal wall.

Glenn R. Gourley, William Mogilevsky, Richard A. Arend, Frank L. Siegel, Gerard B. Odell – 1 July 1985 – Anesthesia‐induced alterations in bilirubin conjugation were studied. Rats were fitted with bile duct and jugular vein catheters while anesthetized with diethyl ether, ketamine or pentobarbital. As anesthesia abated, bile was collected for the next 5 hr and analyzed for flow rate, total bilirubin excretion and bilirubin glucuronide composition. The high‐performance liquid chromatography method used allowed direct analysis of bile without derivatization or extraction.

Peter F. Whitington – 1 July 1985

D. Brian Jones, Michael S. Ching, Richard A. Smallwood, Denis J. Morgan – 1 July 1985 – The highly efficient hepatic extraction of propranolol by the isolated perfused rat liver does not diminish when albumin binding is increased from 30 to 75%. One possible explanation of this insensitivity of propranolol uptake to changes in albumin binding is the mediation of uptake of bound ligand by an albumin receptor on the hepatocyte as postulated for oleate, taurocholic acid and rose bengal.

Charles S. Davidson – 1 July 1985

Thierry Poynard, Claude Degott, Didier Lebrec, Hector Orrego, Yedy Israel, Joan E. Blake, L. M. Blendis, R. Britton, Kim Krogsgaard, Christian Gluud, Jens H. Henriksen, Per Christoffersen – 1 July 1985

Charles Davidson – 1 July 1985

Fred Kern – 1 July 1985

Ding‐Shinn Chen, Juei‐Low Sung, Henry W. Kao, Mary Ashcavai, Allan G. Redeker – 1 July 1985

Thomas Zysset, Mark A. Polokoff, Francis R. Simon – 1 July 1985 – Mechanisms of alcoholic liver disease are still ill defined. We evaluated in two outbred lines of mice whether chronic ingestion of ethanol alters the lipid composition and/or enzyme activity of liver plasma membranes. Two mouse lines with different sensitivities towards the hypnotic effect of ethanol, designated long sleep and short sleep, were fed a liquid diet containing ethanol for 30 days. Ethanol intake reached 30 gm per kg per day in both lines, and serum ethanol levels were similar.