Stephen Holt, John Tulip, Douglas Hamilton, Judith Cummins, Anthony Fields, Catherine Dick – 1 March 1985 – The tumoricidal effect of the activation of hematoporphyrin derivative (HpD), by an argon‐ion‐dye‐laser (wavelength 630 nm), was investigated in the Buffalo rat bearing subcutaneous implants of the Morris 7777 hepatoma. Tumor growth was monitored by measuring the tumor volume with constant force callipers. In control animals and those that were pretreated with HpD alone (10 or 20 mg per kg by i.p.

S. A. Jenkins, J. N. Baxter, W. Corbett, P. Devitt, J. Ware, R. Shields, D. Kravetz, J. Terés, J. Bosch, J. Bruix, J. Rodés – 1 March 1985

A. D'arienzo, D. Mattera, G. Ambrogio, L. Duranti, L. Zeuli, G. Mazzacca, Richard Fuller, Charles L. Hoppel – 1 March 1985

William S. Robinson, Gabriel Garcia – 1 March 1985

Robin M. Walker, William J. Racz, T. Francis McElligott – 1 March 1985 – Acetaminophen‐induced (750 mg per kg p.o.) hepatotoxicity in mice is characterized by hepatomegaly and massive centrilobular congestion which precede the appearance of necrosis. The vascular changes are correlated with the morphologic features using liver hemoglobin content to quantitate erythrocyte sequestration, and hematocrit measurements and 125I‐albumin injections to determine plasma and blood volume.

Sandro Vento, John E. Hegarty, Alfredo Alberti, Charles J. O'brien, Graeme J. M. Alexander, Adrian L. W. F. Eddleston, Roger Williams – 1 March 1985 – Using a newly developed indirect T lymphocyte migration inhibition test, cell‐mediated immunity to HBsAg and HBcAg was directly and simultaneously examined in a total of 21 patients with HBsAg‐positive chronic liver disease (CLD), and in seven subjects whose sera contained anti‐HBs (2 previous acute hepatitis B; 4 hepatitis B vaccine recipients and 1 chronic active hepatitis).

Ira M. Jacobson, Jules L. Dienstag, Barbara G. Werner, Doreen B. Brettler, Peter H. Levine, Isa K. Mushahwar – 1 March 1985 – We tested sera collected between 1976 and 1984 from 362 persons in a variety of epidemiologic categories with acute and chronic hepatitis B and from 76 hemophiliacs and drug addicts with hepatitis B antibodies for hepatitis D markers.

Hiroyuki Shiraishi, Harvey J. Alter, Stephen M. Feinstone, Robert H. Purcell – 1 March 1985 – Convalescent phase non‐A, non‐B (NANB) human and chimpanzee sera were utilized in a solid‐phase radioimmunoassay (RIA) in an attempt to identify a specific NANB antigen in human plasma, plasma‐derived pellets and NP‐40 disrupted pellets proven to transmit NANB infection to chimpanzees. RIA reactivity was noted in 5 of 8 pedigreed NANB infectious plasmas, but did not appear to be virus‐specific.

1 March 1985

Charles S. Davidson, Philip M. Lecompte – 1 March 1985