Prognostic value of serum fibronectin concentration in alcoholic cirrhotic patients

Sylvie Naveau, Thierry Poynard, Annie Abella, Jean‐Pierre Pignon, Alain Poitrine, Hélène Agostini, Othar Zourabichvili, Jean‐Claude Chaput – 1 September 1985 – The aim of this study was to assess prospectively the prognostic value of serum fibronectin in 114 alcoholic cirrhotic patients and to compare serum fibronectin with other prognostic variables. The Cox model and log‐rank test were used to compare survival rates at 1 year.

Acetaminophen hepatotoxicity and targeted rescue: A model for specific chemotherapy of hepatocellular carcinoma

George Y. Wu, Catherine H. Wu, Mark I. Rubin – 1 September 1985 – We have taken advantage of the presence of hepatic receptors for galactose‐terminal (asialo‐)glycoproteins to achieve targeted rescue of differentiated hepatocytes from acetaminophen‐induced toxicity in vitro. To accomplish this, a conjugate was formed by covalent coupling of N‐acetylcysteine (an acetaminophen antagonist) to galactose‐terminal (asialo‐)fetuin.

Polycythemia and the budd‐chiari syndrome: Study of serum erythropoietin and bone marrow erythroid progenitors

Victor Georges Levy, Agnès Ruskone, Claude Baillou, Diana Thierman‐Duffaud, Albert Najman, Georges Albert Boffa – 1 September 1985 – The mechanism of polycythemia associated with the Budd‐Chiari syndrome is unknown. Erythropoiesis in 10 patients with Budd‐Chiari syndrome was studied in an attempt to distinguish prior unrecognized polycythemia vera from secondary polycythemia.

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