Theodore F. Shapero, Irving E. Rosen, Stephanie R. Wilson, Murray M. Fisher – 1 September 1982 – The Sunnybrook Medical Centre Gallstone Study is a randomized, controlled, double‐blind study of chenodeoxycholic acid for dissolution of radiolucent gallstones. Of the first 22 patients whosestones were apparently totally dissolved on oral cholecystography, seven were found to have residual small stone fragments on ultrasound examination of the gallbladder. Continuing chenotherapy was unsuccessful in dissolving these fragments.

R. Palmer BEASLEY, Chia‐Chin Lin, Chia‐Siang Chien, Chien‐Jen Chen, Lu‐Yu Hwang – 1 September 1982 – We tested by radioimmunoassay the sera of 22,707 male Chinese government employees in Taiwan for HBsAg and found 15.2% to be positive. Almost all were confirmed as carriers by follow‐up testing 1 year later. This paper presents HBsAg positivity rates of these men according to the province of China from which they originated, and compares the rates with published provincial mortality rates for primary hepatocellular carcinoma.

Dale A. Schoeller, Alfred L. Baker, Paul S. Monroe, Patricia S. Krager, John F. Schneider – 1 July 1982 – Different methods of expressing the results of the aminopyrine C02 breath test (ABT) were compared to determine the method that would be most sensitive for evaluating liver function.

Harold O. Conn – 1 July 1982

John C. Hoefs, Hanna N. Canawati, Francisco L. Sapico, R. Randy Hopkins, John Weiner, John Z. Montgomerie – 1 July 1982 – Forty‐three patients with spontaneous bacterial peritonitis (SBP) between 1973 and 1978 were identified. Criteria for SBP included a positive ascites culture and polymorphonuclear cell concentration greater than 250 cells per mm3. Chronic liver disease was documented by varices in 91%, severe histologic fibrosis or cirrhosis in 94%, splenomegaly in 91%, and past hospitalization for liver disease in 57% of the patients.

Howard A. Liebman, Barbara C. Furie, Bruce Furie – 1 July 1982

Douglas R. Labrecque, Frank A. Mitros, Radha J. Nathan, Ken G. Romanchuk, George F. Judisch, George H. El‐Khoury – 1 July 1982 – Arteriohepatic dysplasia (AHD) is a multisystem disorder which is characterized by liver, heart, eye, and bony abnormalities. A characteristic facies is also present. The etiology is not clear, and some authors have favored an in utero toxin or infection as the cause. Other reports have shown parent‐to‐child transmission suggesting an autosomal dominant form of inheritance.

Bernard Nordlinger, Michel Parquet, Recaredo Infante, Reginald Moreels, Pol Blondiau, Michele Boschat, Michèle Groussard, Claude Huguet – 1 July 1982 – All of the methods proposed for measuring portal blood flow are either invasive, estimate total rather than nutrient flow, and none has proved reliable in cirrhotic patients. A method has been derived from pharmacokinetic principles used for the calculation of bioavailability of drugs according to the route of administration (i.v. or p.o.) and tested experimentally in 20 pigs.

1 July 1982

James H. Lewis, Hasmukh R. Patel, Hyman J. Zimmerman – 1 July 1982 – The liver is affected in up 50 to 75% of compromised hosts with disseminated Candida albicans infection who come to autopsy. The antemortem diagnosis of hepatic candidiasis is rarely made. Blood cultures are negative in approximately 50% of cases, and biochemical parameters of hepatic injury may be of nonspecific value. Additionally, the more commonly seen renal, cardiac, and respiratory involvement may overshadow the hepatic lesion.