Sophie Lotersztajn, Philippe Mavier, Jeanne Clergue, Daniel Dhumeaux, Françoise Pecker – 1 November 1982 – A high‐affinity calcium‐stimulated ATPase (Ca‐ATPase) was identified in a plasma membrane subcellular fraction from human liver.
Peter Thomas, Carol A. Toth, Norman Zamcheck – 1 November 1982 – The transport of human α1‐acid glycoprotein from the circulation to the bile has been studied in the rat. Biliary excretion was proportional to the i.v. injected dose, and the percentage excreted remained constant. The amount excreted in the bile (over 4 hr) was inversely related to the rate of hepatic (hepatocyte) uptake and the galactose receptor which is specific for asialo glycoproteins was not involved.
1 November 1982
Raphael Pollack, Shaindel Y. Mishkin, Harold P. Morris, Mordechai A. Yalovsky, Seymour Mishkin – 1 November 1982 – The objective of these studies was to elucidate further the mechanisms of the thyroid dependency of Morris Hepatoma 44. In vivo experiments indicated that while exogenous thyroxine (8 μg per kg) reversed the hypothyroid‐mediated inhibition of primary hepatoma growth, no such effect was noted with the administration of ovine prolactin (100 μg per kg s.c.) and bovine growth hormone (100 μg per kg, s.c).
Enrico Roda, Franco Bazzoli, Antonio M. Morselli Labate, Giuseppe Mazzella, Aldo Roda, Claudia Sama, Davide Festi, Rita Aldini, Francesco Taroni, Luigi Barbara – 1 November 1982 – Cholesterol gallstones are dissolved in man by chenodeoxycholic acid (CDCA) and ursodeoxycholic acid (UDCA). To test the comparative efficacy of these two cholelitholytic bile acids, 223 gallstone patients were randomly treated with either UDCA or CDCA at two different doses: 7 to 8 mg per kg per day and 14 to 15 mg per kg per day.
S. Victor Feinman, Lacy R. Overby, Barnet Berris, Kurt Chau, Charles A. Schable, James E. Maynard – 1 November 1982 – IgM antibody to hepatitis B core antigen (IgM anti‐HBc) was determined in 60 patients whose serum was positive for hepatitis B surface antigen (HBsAg) and 18 patients whose serum was negative for HBsAg, but positive for antibody to hepatitis B core antigen (anti‐HBc). Two radioimmunoassays were done utilizing either anti‐u antibody to capture IgM or Staphylococcus A protein to separate IgG and IgM.
Pui C. Wu, Ching L. Lai, Kui C. Lam, Joana Ho – 1 November 1982 – To study the value of corticosteroids in HBsAg‐positive chronic active hepatitis, 18 pairs of liver histology comprising 36 liver biopsies from a prospective, randomized, controlled trial were evaluated. The median interval between the initial and follow‐up histology was 8 1/2 months in 8 patients given prednisolone and 8 1/4 months in 10 patients given placebo tablets.
Albert L. Jones, Sandra Huling, Gary T. Hradek, Henry S. Gaines, William D. Christiansen, Brian J. Underdown – 1 November 1982 – It is well documented that the liver provides an important source of secretory immunoglobulin A (sIgA) in the gut fluid. In the rat, liver parenchymal cells can actively sequester the dimeric form of IgA (dIgA) from plasma and transfer it attached to its receptor, secretory component (SC), via vesicles into the bile.