Amador Schüller, Jorge Moscat, Emilio Diez, Jose C. Fernandez‐Checa, Francisco G. Gavilanes, Angel M. Municio – 1 July 1985 – Gluconeogenesis and palmitate incorporation into triacylglycerols and phosphatidylcholine were measured in isolated hepatocytes from control and ethanol‐treated rats. Basal gluconeogenesis and its hormonal response decreased in hepatocytes from ethanol‐treated animals; palmitate incorporation into triacylglycerols increased.

Frank L. Iber – 1 July 1985

L. Ortega, J. I. Landa Garcia, A. Torres Garcia, G. Silecchia, J. Arenas, A. Suarez, M. Moreno Azcoitia, J. Sanz Esponera, E. Moreno Gonzalez, J. L. Balibrea Cantero – 1 July 1985 – Results concerning morphological and biochemical changes following intravenous administration of different doses of acetaminophen in dogs are reported. Acetaminophen infusion, as a parenteral solution (500 mg per kg per 90 min), produced fulminant hepatitis characterized by a good correlation between Portmann's grade of lesion and percentage of necrosis. All animals died within 76 hr after intoxication.

Eliezar A. Dawidowicz – 1 July 1985

Vital A. Mesa, Johan Fevery, Karel P. M. Heirwegh, Jan De Groote – 1 July 1985 – Bilirubin seems to share the biliary excretion pathway with other organic anions, but not with bile acids. We studied the effects of the organic anion ioglycamide, an iodinated contrast agent, on bilirubin metabolism in Wistar rats. This compound does not undergo conjugation and is characterized by a maximal biliary secretory rate (Tm).

E. Wisse, R. B. de Zanger, K. Charels, P. van der Smissen, R. S. McCuskey – 1 July 1985

Daniel S. Matloff – 1 July 1985

1 July 1985

Geoffrey Dusheiko, Adrian Dibisceglie, Sheila Bowyer, Evelyn Sachs, Marian Ritchie, Barry Schoub, Michael Kew – 1 July 1985 – We have investigated the efficacy of a relatively prolonged course of recombinant leukocyte interferon treatment in 14 chronic HBsAg‐, HBeAg‐, hepatitis B virus DNA‐ and DNA polymerase‐positive carriers. α‐Interferon was administered for 9 weeks. Six of 14 treated carriers have a sustained loss of HBeAg, hepatitis B virus DNA and DNA polymerase. Four subsequently lost HBsAg (28.5%).

Michèle Corbic, Cristina Muñoz, Micheline Dumont, Ghislaine De Couët, Serge Erlinger – 1 July 1985 – The effect of acute metabolic or respiratory acid‐base disturbances on biliary bicarbonate secretion was examined in bile fistula rats. Animals were infused with ursodeoxycholate at a rate that stimulates bicarbonate secretion (1 μmole · min−1 · 100 gm−1), in control conditions and during acute acid‐base disturbances.