Effect of chronic ethanol ingestion on hepatic and intestinal acyl coenzyme A:Cholesterol acyltransferase and 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase in the rat
F. Jeffrey Field, John S. Boydstun, Douglas R. Labrecque – 1 January 1985 – Two groups of rats were pair‐fed diets in which 36% of the calories were provided by either ethanol or dextrimaltose. After 60 days on these liquid diets, rats fed ethanol were significantly smaller than control rats fed dextrimaltose. Serum cholesterol levels in ethanol‐fed animals were 20% higher than control rats. Cholestasis was not observed histologically, and serum alkaline phosphatase and bilirubin levels were the same in both groups.
The merck index. An encyclopedia of chemicals, drugs, and biologicals. Tenth Edition. Martha Windholz, Editor; Susan Budavari, Co‐Editor; Rosemary F. Blumetti, Associate Editor, Elizabeth S. Otterbein, Assistant Editor. 2, 067 pp. (including tables and in
Michael A. Marletta – 1 January 1985
Hepatic injury in the toxic oil syndrome
F. Diaz De Rojas, M. Castro Garcia, I. Abaitua Borda, M. Posada De La Paz, J. M. Tabuenca Oliver, J. A. Solis‐Herruzo, G. Castellano, F. Colina, J. D. Morillas, M. T. Muñoz‐Yagüe, J. V. Vidal – 1 January 1985
Insulin action in cirrhosis
R. Taylor, R. J. Heine, J. Collins, O. F. W. James, K. G. M. M. Alberti – 1 January 1985 – In vivo insulin sensitivity and adipocyte insulin binding and action were assessed in 16 patients with histologically proven hepatic cirrhosis and 11 age‐, weight‐ and sex‐matched normal control subjects. The cirrhotic group displayed impaired oral glucose tolerance, despite an exaggerated serum immunoreactive insulin response, and in vivo insulin resistance as assessed both by the euglycemic hyperinsulinemic clamp and the glucose‐insulin infusion techniques.
Biliary proteins and ductular ultrastructure
Irmin Sternlieb, Nelson Quintana – 1 January 1985
Masthead
1 January 1985
Effects of dexamethasone on albumin and collagen gene expression in primary cultures of adult rat hepatocytes
Douglas M. Jefferson, Lola M. Reid, Marie‐Adele Giambrone, David A. Shafritz, Mark A. Zern – 1 January 1985 – To further our studies on collagen gene expression, we have evaluated the molecular basis for the finding that steroids decrease collagen synthesis in cultured hepatocytes. We studied the effects of dexamethasone on primary cultures of adult rat hepatocytes grown on tissue culture plastic in either serum‐supplemented medium or a serum‐free hormonally defined medium.
Prevalence of hbeag and anti‐hbe in chronic active hepatitis, cirrhosis and primary hepatocellular carcinoma in korea
Chung‐Yong Kim, Soon‐Kee Bae, Hie‐Won L. Hann, W. Thomas London, Baruch S. Blumberg – 1 January 1985 – The prevalence of HBeAg was studied in Korean patients with chronic active hepatitis, cirrhosis and primary hepatocellular carcinoma. There is an independent association of HBeAg prevalence with age and diagnosis. These findings are discussed in terms of a developmental model for primary hepatocellular carcinoma which could explain the lower frequency of HBeAg in the cancer cases.
Pattern and prognosis of liver function test abnormalities during parenteral nutrition in inflammatory bowel disease
Jose M. Bengoa, Stephen B. Hanauer, Michael D. Sitrin, Alfred L. Baker, Irwin H. Rosenberg – 1 January 1985 – The pattern of liver function test abnormalities was examined during total parenteral nutrition (TPN), using both dextrose and fat emulsions as caloric sources, in 92 patients with inflammatory bowel disease. Seventy‐two patients had completely normal tests before TPN while 20 had one or more abnormal liver function tests before TPN was started. Serum bilirubin levels were normal in all patients before TPN; within 2 weeks on TPN, 25% of patients had elevated bilirubin levels.