A. Jasmine Bullard, Francesca E. Cunningham, Bryan D. Volpp, Elliott Lowy, Lauren A. Beste, Bernadette B. Heron, Mark Geraci, Julia M. Hammond, Kourtney LaPlant, Elise A. Stave, Marsha J. Turner, Meghan C. O’Leary, Michael J. Kelley, Christine M. Hunt – 28 August 2018 – Hepatitis B virus (HBV) reactivation may occur with high risk immunosuppression, such as anti‐cluster of differentiation (CD)20 antibodies (Abs). Appropriate HBV prophylaxis during anti‐CD20 Ab therapy averts hepatitis, chemotherapy disruption, and death.

Ann Robinson, Hesam Tavakoli, Benny Liu, Taft Bhuket, Robert J. Wong – 28 August 2018 – Individuals from the 1945‐1965 birth cohort account for the majority of hepatocellular carcinoma (HCC) cases in the United States. Understanding trends in HCC among this birth cohort is vital given the increasing burden of chronic liver disease among this group. We retrospectively evaluated trends and disparities in HCC tumor stage at the time of diagnosis among the 1945‐1965 birth cohort in the United States using the Surveillance, Epidemiology, and End Results (SEER) cancer registry.

Ravi Sujan, Monica Cruz‐Lemini, Jose Altamirano, Douglas A. Simonetto, Rakhi Maiwall, Page Axley, Taylor Richardson, Vivek Desai, Joaquin Cabezas, Victor Vargas, Patrick S. Kamath, Vijay H. Shah, Shiv K. Sarin, Ramon Bataller, Ashwani K. Singal – 28 August 2018 – Identifying patients at high risk for acute kidney injury (AKI) during hospitalization among patients admitted with severe alcoholic hepatitis (AH) is an unmet clinical need. We performed a multicentric prospective cohort study using data from 4 different cohorts on well‐characterized patients hospitalized with severe AH.

Li Yang, Ying Zhou, Pei‐pei Xu, Reena Mourya, Hai‐yan Lei, Guo‐qing Cao, Xiao‐li Xiong, Hui Xu, Xu‐fei Duan, Na Wang, Lin Fei, Xiao‐pan Chang, Xi Zhang, Meng Jiang, Jorge A. Bezerra, Shao‐tao Tang – 28 August 2018 – The diagnosis of biliary atresia (BA) remains a clinical challenge because affected infants have signs, symptoms, and serum liver biochemistry that are also seen in those with other causes of neonatal cholestasis (non‐BA). However, an early diagnosis and prompt surgical treatment are required to improve clinical outcome.

Andrew J. Muir, Cynthia Levy, Harry L.A. Janssen, Aldo J. Montano‐Loza, Mitchell L. Shiffman, Stephen Caldwell, Velimir Luketic, Dora Ding, Catherine Jia, Bryan J. McColgan, John G. McHutchison, G. Mani Subramanian, Robert P. Myers, Michael Manns, Roger Chapman, Nezam H. Afdhal, Zachary Goodman, Bertus Eksteen, Christopher L. Bowlus, for the GS‐US‐321‐0102 Investigators – 28 August 2018 – Lysyl oxidase like‐2 (LOXL2) plays a central role in fibrogenesis and is elevated in the serum and liver of patients with primary sclerosing cholangitis (PSC).

Yongsheng Li, Daniel J. McGrail, Juan Xu, Junyi Li, Ning‐Ning Liu, Ming Sun, Richard Lin, Rita Pancsa, Jiwei Zhang, Ju‐Seog Lee, Hui Wang, Gordon B. Mills, Xia Li, Song Yi, Nidhi Sahni – 28 August 2018 – The interaction between RNA‐binding proteins (RBPs) and RNA plays an important role in regulating cellular function. However, decoding genome‐wide protein–RNA regulatory networks as well as how cancer‐related mutations impair RNA regulatory activities in hepatocellular carcinoma (HCC) remains mostly undetermined.

Andrew J. Muir, Cynthia Levy, Harry L.A. Janssen, Aldo J. Montano‐Loza, Mitchell L. Shiffman, Stephen Caldwell, Velimir Luketic, Dora Ding, Catherine Jia, Bryan J. McColgan, John G. McHutchison, G. Mani Subramanian, Robert P. Myers, Michael Manns, Roger Chapman, Nezam H. Afdhal, Zachary Goodman, Bertus Eksteen, Christopher L. Bowlus, for the GS‐US‐321‐0102 Investigators – 28 August 2018 – Lysyl oxidase like‐2 (LOXL2) plays a central role in fibrogenesis and is elevated in the serum and liver of patients with primary sclerosing cholangitis (PSC).

Jonggi Choi, Gi‐Ae Kim, Seungbong Han, Woochang Lee, Sail Chun, Young‐Suk Lim – 28 August 2018 – We aimed to determine the surveillance performance of alpha‐fetoprotein (AFP), lectin‐reactive AFP (AFP‐L3), des‐gamma‐carboxy prothrombin (DCP), and their combinations for the early detection of hepatocellular carcinoma (HCC) by using prospectively collected longitudinal samples in patients at risk.

Stefania Mantovani, Barbara Oliviero, Andrea Lombardi, Stefania Varchetta, Dalila Mele, Angelo Sangiovanni, Giorgio Rossi, Matteo Donadon, Guido Torzilli, Cristiana Soldani, Camillo Porta, Paolo Pedrazzoli, Silvia Chiellino, Roberto Santambrogio, Enrico Opocher, Marcello Maestri, Stefano Bernuzzi, Armando Rossello, Sophie Clément, Claudio De Vito, Laura Rubbia‐Brandt, Francesco Negro, Mario U. Mondelli – 28 August 2018 – The activating natural cytotoxicity receptor NKp30 is critical for natural killer (NK) cell function and tumor immune surveillance.

Giovanna Ferraioli – 28 August 2018