A Prospective Randomized Study of Two Sclerotherapy Techniques for Esophageal Varices
David Westaby, Brian R. D. Macdougall, Walter Melia, Andrew Theodossi, Roger Williams – 1 January 1983 – In a study designed to compare the efficacy and safety of two techniques of injection sclerotherapy, 40 patients (30 with cirrhosis and 10 with portal vein block) were randomly allocated to the sheath or free‐hand technique. Although the former was associated with significantly less bleeding within the first 24 hr of injection (p < 0.05) but more postinjection pain (p < 0.05) and esophageal stricture, there was a trend toward earlier obliteration of varices.