International Workshop on (+)‐Cyanidanol‐3 in Diseases of the Liver. Royal Society of Medicine International Congress and Symposium Series No. 47. Held in Crans‐Montana, Switzerland. Edited by H. O. Conn. 267 pp. London: Academic Press Inc. and New York:

Hepatitis A Infection in Chronic Carriers of Hepatitis B Virus

Reinhart Zachoval, Michael Roggendorf, Friedrich Deinhardt – 1 January 1983 – By routine screening for serologic markers of hepatitis A and B in patients with acute hepatitis, 30 chronic carriers of hepatitis B virus with serologic evidence of acute hepatitis A and two patients with simultaneous acute infection with hepatitis A virus and hepatitis B virus were detected.

Problems in Treating Experimentally Induced Acute Hepatic Failure by Hemoperfusion or Cross Circulation

Robert A. F. M. Chamuleau, Robert J. Popken, Ellen C. Beyerbacht, Henk W. M. De Koning – 1 January 1983 – Acute hepatic failure was induced in rats by galactosamine injection intraperitoneally (1 gm per kg). Twenty‐four hours later rats were treated by hemoperfusion (HP) over encapsulated sorbents: cellulose acetate‐coated charcoal, polyelectrolyte‐coated XAD4, a combination of both, or cross circulation with a healthy donor. Compared with control treatment (prevention of hypoglycemia by glucose infusion), the survival rate was not improved by HP or cross circulation: controls 19% vs.

Conversion of Micronodular Cirrhosis into Macronodular Cirrhosis

Lis Fauerholdt, Poul Schlichting, Erik Christensen, Hemming Poulsen, Niels Tygstrup, Erik Juhl, The Copenhagen Study Group FOR Liver Diseases – 1 January 1983 – The conversion from micro‐ to macronodular cirrhosis is claimed to be a general phenomenon. In this study, the conversion was quantitated by means of liver needle follow‐up biopsies and autopsy in 156 patients followed in a controlled clinical trial of prednisone treatment in cirrhosis.

Sex Difference in Chronic Hepatitis B Virus Infection: An Appraisal Based on the Status of Hepatitis B e Antigen and Antibody

Chia‐Ming Chu, Yun‐Fan Liaw, I‐Shyan Sheen, Deng‐Yn Lin, Miau‐Ju Huang – 1 January 1983 – Hepatitis B e antigen (HBeAg) and antibody (anti‐HBe) were studied by radioimmunoassay in consecutive series of 145 asymptomatic hepatitis B surface antigen (HBsAg) carriers, 389 patients with HBsAg‐positive chronic liver disease and 194 patients with HBsAg‐positive hepatocellular carcinoma, and compared between male and female subjects. The male to female ratio increased from 1.2 in asymptomatic carriers to 6.3 in chronic liver disease and 9.8 in hepatocellular carcinoma.

Exudative Ascites in the Course of Acute Type B Hepatitis

Carmen Viola, Lydia Vineta, Jaime Bosch, Juan Rodés – 1 January 1983 – Two patients who presented with an exudative ascites in the course of typical acute type B hepatitis are reported. In one of them, ascites was associated with an exudative pleural effusion. In both patients, the clinical course of the hepatitis was uneventful, and ascites and pleural effusion disappeared spontaneously. Portal hypertension and common causes of exudative ascites were excluded.

Arteriohepatic Dysplasia. II. Hepatobiliary Morphology

Ellen I. Kahn, Fredric Daum, James Markowitz, Harvey W. Aiges, Keith M. Schneider, Henry B. So, Peter Altman, Roma S. Chandra, Mervin Silverberg – 1 January 1983 – Five children were noted to have arteriohepatic dysplasia (Alagille's syndrome) between 3 and 7 months of age. Prior to diagnosis, four underwent Kasai procedures after intraoperative cholangio‐grams failed to demonstrate patency of the extrahepatic bile ducts. In three patients, a focal proximal hypoplasia of the common hepatic duct was demonstrated with fibrosis and increased vascularity.

In Vivo and Electron Microscopic Observations of the Hepatic Micro vasculature in the Rat Following Portacaval Anastomosis

Robert S. Mccuskey, Franz J. Vonnahme, Martin Grun – 1 January 1983 – The livers of rats subjected to end‐to‐side portacaval anastomoses were studied 3 to 5 months postoperatively by in vivo and electron microscopy. Compared with sham‐operated controls, the livers of portacaval anastomoses animals contained dilated, tortuous networks of sinusoids. The velocity of blood flow in these vessels tended to be slower and more variable than controls, but always progressed toward the hepatic venules.

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