Anne‐Marie Durand‐Schneider, Michèle Maurice, Micheline Dumont, Gérard Feldmann – 1 November 1987 – The hepatocyte plasma membrane presents a morphological and functional regionalization into three domains: the sinusoidal; the lateral, and the canalicular. The mechanisms responsible for the biogenesis and maintenance of this regionalization are poorly understood. In this work, we have used colchicine and phalloidin, two drugs known to interfere with the secretory processes in hepatocytes, to study whether they also affect the transport of membrane proteins.

Harold O. Conn – 1 November 1987

Willis C. Maddrey – 1 November 1987

Henk F. J. Hendriks, Adriaan Brouwer, Dick L. Knook – 1 November 1987

Paul Genecin – 1 November 1987

Ramjeet S. Pemsingh, Brian R. Macpherson, Gerald W. Scott – 1 November 1987 – This study identified mucus granules, determined mode of release and quantified their volume in the gallbladder epithelium of Richardson's ground squirrels (Spermophilus richardsonii) fed a lithogenic diet of 2% cholesterol to experimentally induce gallstone formation. Tissue was examined using light microscopy histochemistry, scanning and transmission electron microscopy, as well as autoradiography and morphometry at the electron microscopic level.

Herbert L. Bonkovsky, John F. Healey, Beth Lincoln, Bruce R. Bacon, David F. Bishop, George H. Elder – 1 November 1987 – Rats fed chow containing finely divided elemental iron (from carbonyl‐iron) develop hepatic iron overload resembling human hereditary hemochromatosis in that deposition of iron is primarily in periportal hepatocytes and with hepatic iron concentrations sufficiently high to be associated in the human disease with hepatic fibrosis or cirrhosis.

Peter N. Burns, Lynwood Hammers – 1 November 1987 – FM sonography—a signal‐processing technique that uses frequency and phase information as well as amplitude data—shows promise in evaluation of patients with diffuse liver disease. In a prospective blinded review of 37 patients with biopsyproved liver disease and 42 healthy volunteers, FM sonography was clearly superior to traditional amplitude‐based (AM) sonography in distinguishing healthy from diseased subjects.

Murray Epstein, Meyer Lifschitz – 1 November 1987

Peter G. Traber, Mauro Dal Canto, Daniel R. Ganger, Andres T. Blei – 1 November 1987 – Brain edema is a major complication of fulminant hepatic failure and is responsible for death in a large percentage of patients. We previously demonstrated the progressive accumulation of water in grey matter areas of the brain in the rabbit with galactosamine‐induced fulminant hepatic failure.