Renal eicosanoids as determinants of renal function in liver disease
Murray Epstein, Meyer Lifschitz – 1 November 1987
Electron microscopic evaluation of brain edema in rabbits with galactosamine‐induced fulminant hepatic failure: Ultrastructure and integrity of the blood‐brain barrier
Peter G. Traber, Mauro Dal Canto, Daniel R. Ganger, Andres T. Blei – 1 November 1987 – Brain edema is a major complication of fulminant hepatic failure and is responsible for death in a large percentage of patients. We previously demonstrated the progressive accumulation of water in grey matter areas of the brain in the rabbit with galactosamine‐induced fulminant hepatic failure.
Increase in the number of fenestrae in mouse endothelial liver cells by altering the cytoskeleton with cytochalasin B
Anne‐Marie Steffan, Jean‐Louis Gendrault, André Kirn – 1 November 1987 – Endothelial cells of the hepatic sinusoid isolated from mice livers and maintained in culture display typical fenestrae grouped in sieve plates. Treatment with cytochalasin B led to no significant change in the mean diameter of the fenestrae but to an increase in their number and in the porosity of the cells (percentage of the cellular surface opened by the fenestrae) which attained up to 300% of that of the controls.
Graft‐versus‐host‐induced cirrhosis: Possible mechanisms
Howard M. Shulman – 1 November 1987 – A 28‐yr‐old woman with severe idiopathic aplastic anemia received an HLA‐identical mixed lymphocyte culture nonreactive bone marrow transplant from her brother. In the months after successful engraftment, she developed cutaneous and hepatic graft‐versus‐host disease, associated with marked cholestatic jaundice. Despite a series of therapeutic maneuvers, cholestasis persisted but remained relative stable over the enuing 10 yr. However, serial liver biopsies revealed progressive biliary‐type firbrosis culminating in cirrhosis.
Elsewhere correspondence
Stuart E. Lind, Daniel E. Singer, Klemens B. Meyer, Jerome P. Kassirer – 1 November 1987
The epidemiology and clinical outcome of hepatitis D virus (delta) infection in Jordan
Ala U. Toukan, Omayma A. Abu‐El‐Rub, Salwa A. Abu‐Laban, Musleh S. Tarawneh, M. Feisal Kamal, Stephen C. Hadler, Krzysztof Krawczynski, Harold S. Margolis, James E. Maynard – 1 November 1987 – The epidemiology and clinical outcome of hepatitis D viral infection in HBsAg‐positive acute hepatitis, chronic liver disease, primary hepatocellular carcinoma and the symptomless carrier state was studied in Jordan.
Bile pigments and jaundice: Molecular, metabolic and medical aspects. Edited by J. Donald Ostrow. 744 pp. New York: Marcel Dekker, Inc., 1986. $119.50
Harold O. Conn, Johan Fevery – 1 September 1987
Hepatitis B vaccination of newborn infants: Clinical study of new vaccine formulation and dose regimen
Keun Soo Lee, Hahng Lee, Soo Jee Moon, Kyu Jong Choi, Ki Hong Kim, Chun Won Kim, Wha Soon Chung, Tae Yael Choi – 1 September 1987 – To investigate the efficacy in anti‐HBsAg response with half the recommended adult dose in a standard vaccination schedule or with a full dose in reduced number of vaccination schedule, 201 healthy newborn infants were randomized to receive either 2.5 μg Hevac B vaccine at birth [1, 2 and 14 months in Group I (101)] or 5 μg at birth [2 and 14 months in Group II (100)]. Anti‐HBsAg responses in the two groups were compared.