Kenji Fujiwara, Itsuro Ogata, Yasuhiko Ohta, Shigeki Hayashi, Shunji Mishiro, Katsuyoshi Takatsuki, Yuzuru Sato, Shinwa Yamada, Keichi Hirata, Hiroshi Oka, Toshitsugu Oda, Hisanori Kawaji, Shinobu Matsuda, Yasuhiko Niiyama, Ryoichi Tsukuda – 1 July 1988 – Hepatic fibrosis was induced in rats by repeated i.p. injections of pig serum. The hepatic hydroxyproline content increased to 2.1 times the normal control level at 6 weeks and to 3.2 times at 10 weeks.

Jordi Camps, Xavier Sola, Antoni Rimola, Albert Parés, Antoni Rives, Juan M. Salmeron, Vicente Arroyo, Joan Rodés – 1 July 1988 – Several authors have suggested that the risk of developing aminoglycoside nephrotoxicity is greater in cirrhotic patients than in the noncirrhotic population. However, this has not been confirmed by other investigators. To compare the intensity and characteristics of aminoglycoside nephrotoxicity in cirrhotic and normal rats, 31 rats with carbon tetrachloride‐induced cirrhosis with ascites and 35 control rats were treated with gentamicin.

Roland Schachler, Tilman Sauerbruch, Ulrich Wosiewitz, Joseph Holl, Dietbert Hahn, Roland Denk, Michael Neubrand, Gustav Paumgartner – 1 July 1988 – Eighty in vitro experiments were performed with single (n = 51) or multiple (n = 29) gallstones in order to find out which parameters are of prime importance for their disintegration by extracorporeal shock waves. A Dornier lithotripter and an upper limit of 1,500 discharges were employed.

Ian R. Wanless – 1 July 1988

Toshikazu Uchida, Koyu Suzuki, Yasunori Okuda, Toshio Shikata – 1 July 1988 – An attempt was made to infect primary duck hepatocyte cultures with duck hepatitis B virus in vitro in order to clarify the biology of hepatitis B virus. Livers of ducklings, 0 to 17 days posthatch, without viremia were digested ex situ by perfusion of collagenase solution through the portal or hepatic vein.

Y. Peled, Z. Halpern, R. Baruch, G. Goldman, T. Gilat – 1 July 1988 – This study was performed to determine whether biliary cholesterol nucleates primarily from vesicles or micelles. Twenty gallbladder biles and 12 hepatic biles from patients with gallstones as well as 16 model biles were examined. The nucleation times (days) of the biles as well as their isolated vesicular and micellar fractions were determined and their lipid composition was analyzed. In 41 of 46 comparisons, cholesterol nucleated faster from vesicles than micelles; in only one case was the opposite found.

Willis C. Maddrey, David H. Van Thiel – 1 July 1988

David Y. Graham – 1 July 1988

1 July 1988

Yoram Bujanover, Sergio Amarri, Emanuel Lebenthal, James K. Petell – 1 July 1988 – The regulation of different maturational processes in the liver is believed to be influenced by the hormonal system. The aim of this study was to investigate the effect of two hormones, glucagon and dexamethasone, on levels of plasma membrane proteins in rat liver cells during late fetal and early postnatal stages of development.