Esteban Mezey, James J. Potter, Deborah L. Rhodes – 1 November 1986 – The effect of growth hormone on the activity of alcohol dehydrogenase was determined in hepatocyte culture from normal and hypophysectomized male rats. Alcohol dehydrogenase activity was highest in hepatocytes harvested from hypophysectomized rats. The enzyme activity remained stable in hepatocytes harvested from normal rats during 2 to 6 days of culture but declined steadily in hepatocytes cultured from hypophysectomized rats.

Marcus A. Rothschild, Murray Oratz, Sidney S. Schreiber, Joseph Mongelli – 1 November 1986 – Sucrose and ethanol inhibit albumin synthesis; sucrose via an osmotic mechanism and ethanol during its metabolism. The present study was undertaken to compare the effects of both of these agents on albumin synthesis and secretion, and to see if ethanol inhibition could be related to an osmotic effect.

Sien‐Sing Yang, Nai‐Shin Chu, Yun‐Fan Liaw – 1 November 1986 – Brainstem auditory evoked potentials were obtained from 30 patients primarily with viral hepatitis to determine the functional status of the brainstem in hepatic encephalopathy. The patients were divided into four groups: Group 1 with compensated hepatic diseases; Group 2 with hepatic failure but no hepatic encephalopathy; Group 3 with Grade 1 or 2 hepatic encephalopathy, and Group 4 with Grade 3 or 4 hepatic encephalopathy.

William R. Treem, Camillus A. Witzleben, David A. Piccoli, Charles A. Stanley, Daniel E. Hale, Paul M. Coates, John B. Watkins – 1 November 1986 – The clinical and pathologic findings in 12 patients with medium‐chain acyl CoA dehydrogenase deficiency and three patients with long‐chain acyl CoA dehydrogenase deficiency are summarized. Although these inborn errors of intramitochondrial β‐oxidation of fatty acids present with similar findings to Reye's syndrome, there are clinical, laboratory and hepatic histologic differences.

1 November 1986

Colin E. Atterbury – 1 November 1986

Swan N. Thung, Michael A. Gerber, Efthimios J. Kasambalides, Bal K. Gilja, William Keh, Wolfram H. Gerlich – 1 November 1986 – The large (pre‐S1), middle (pre‐S2) and major (P24) polypeptides of HBsAg have been defined in detail, but their role in hepatitis B virus infection is not known. Therefore, we studied the expression of pre‐S1, pre‐S2 and P24 in the liver of 15 patients with acute or chronic hepatitis B virus infection using monoclonal and polyclonal antibodies in a double staining immunofluorescence method.

Angelika Vallbracht, Peter Gabriel, Katharina Maier, Franz Hartmann, Hans Jörg Steinhardt, Claudia Müller, Alexis Wolf, Klaus Herbert Manncke, Bertram Flehmig – 1 November 1986 – We studied cell‐mediated cytotoxicity to hepatitis A virus‐infected cells in seven patients with acute type A hepatitis and two controls. Skin fibroblast cultures obtained from the skin biopsies of seven patients after acute hepatitis A virus infection and from two persons without history of current or past hepatitis A virus infection were inoculated with hepatitis A virus.

Giorgio Verme, Pietro Amoroso, Gennaro Lettieri, Paola Pierri, Ezio David, Fausto Sessa, Roberto Rizzi, Ferruccio Bonino, Serafino Recchia, Mario Rizzetto – 1 November 1986 – The histopathology of hepatitis delta virus disease was studied in carriers of HBsAg with chronic hepatitis delta antigen‐positive hepatitis and in serial biopsies of patients with acute hepatitis delta virus hepatitis that progressed to chronicity.

Bernardo Buitrago, Stephen C. Hadler, Hans Popper, Swan N. Thung, Michael A. Gerber, Robert H. Purcell, James E. Maynard – 1 November 1986 – “Santa Marta” hepatitis has been recognized as an unusual type of severe hepatitis occurring in northern Colombia since 1930. Liver specimens from a historic viscerotomy series, used by Gast‐Galvis to identify cases and describe epidemiologic features of this disease, were available for review and histopathologic staining for δ‐virus.