Jay H. Hoofnagle – 1 May 1987 – A double‐blind, randomized, controlled trial has been undertaken to evaluate treatment of chronic hepatitis type B with levamisole. Ten patients received levamisole (150 mg/day, 3 days/wk) and 10 received placebo until seroconversion to antibody to hepatitis B e antigen eventually occurred, or for a maximum of 18 mo.
Richard A. Willson, K. J. Clayson, S. Leon – 1 May 1987
Osamu Nishida, Fuminori Moriyasu, Takefumi Nakamura, Nobuyuki Ban, Kensuke Miura, Masahiko Sakai, Haruto Uchino, Takeo Miyake – 1 May 1987 – We examined the hemodynamic changes induced by transient splenic arterial occlusion using a balloon catheter to investigate the hemodynamic effect of transcatheter splenic arterial embolization—a procedure that has been used since its introduction in 1973 as therapy for hypersplenism and more recently for portal hypertension.
Gretchen M. Hill, George J. Brewer, Ananda S. Prasad, Connie R. Hydrick, Deborah E. Hartmann – 1 May 1987 – The standard therapy for preventing copper accumulation in Wilson's disease, D‐penicillamine, has been a life‐saving drug, but it has many side effects and some patients are completely intolerant. We have been using oral zinc as another approach to the therapy for Wilson's disease, with copper balance studies as the key initial assessment of the adequacy of a given dose or regimen of zinc therapy.
Esteban Celis, Katalin G. Abraham, Richard W. Miller – 1 May 1987 – Antibodies to HBsAg of IgG class enhanced the helper activity of a human T cell clone to promote the in vitro synthesis of immunoglobulins by autologous B lymphocytes. Using two different assay systems, the effect of antigen‐specific antibodies on the helper function of a HBsAg‐reactive T cell clone was studied. The monoclonal antibody to HBsAg A5C3 (IgG) increased significantly the T cell‐dependent production of immunoglobulins by Staphyloccocus aureus‐stimulated autologous B lymphocytes.
Maria H. Sjogren, Jay H. Hoofnagle, Jeanne G. Waggoner – 1 May 1987 – Serum levels of antibody to hepatitis B core antigen and IgM antibody to hepatitis B core antigen were tested in 15 patients who participated in a randomized, placebo‐controlled trial of a 28‐day course of prednisolone therapy. During treatment, serum levels of antibody to hepatitis B core antigen and IgM antibody to hepatitis B core antigen decreased in all 10 treated patients, but in none of five controls (p < 0.05).
Lawrence Deckelbaum – 1 May 1987 – Patients with obstructive jaundice are susceptible to postoperative shock and kidney failure. The cause of these potentially fatal complications has not been fully clarified. The present study was designed to assess the role of myocardial dysfunction in the hemodynamic disturbance of obstructive jaundice. We studied the effect of isolated cholemia on left ventricular performance in five conscious dogs before and 2 weeks after choledochocaval anastomosis by using measurements of systolic time intervals (STIs) and maximal dp/dt.
James S. Morgan, Harold O. Conn – 1 May 1987
Kevin D. Mullen – 1 May 1987