Joseph M. Guattery, William W. Faloon – 1 July 1987 – The repeated observation of a fall in serum enzymes at midmenstrual cycle in an untreated patient with primary biliary cirrhosis stimulated a study of estrogen administration in five patients with primary biliary cirrhosis. One patient was premenopausal, one patient was postmenopausal and three had had oophorectomy. After 2 weeks of ethinyl estradiol, AST was under 100 IU per dl in all and had decreased by 50% or more in 4 of 5 patients.

Richard B. Jennett, Dean J. Tuma, Michael F. Sorrell – 1 July 1987 – Immunization of mice with acetaldehyde conjugated to human plasma proteins resulted in the production of polyclonal antibodies that reacted with erythrocyte protein‐acetaldehyde conjugates, but not with control erythrocyte proteins. Such antibodies recognized erythrocyte protein‐acetaldehyde conjugates prepared with 20–100 μM acetaldehyde, concentrations that exist in the blood of alcoholics. The antibodies also recognized acetaldehyde condensation products with synthetic poly‐(L‐lysine).

Sugantha Govindarajan, Cynthia C. Nast, William L. Smith, Martin A. Koyle, George Daskalopoulos, Robert D. Zipser – 1 July 1987 – To evaluate possible causes of the diminished prostaglandin production in advanced hepatorenal syndrome, prostaglandin endoperoxide synthase and prostacyclin synthase were localized and semiquantitated by immunofluorescence in postmortem, biopsy and nephrectomy renal tissues. In normal kidneys, antiprostacyclin synthase serum caused intense staining in peritubular capillaries, in the adjacent renal interstitial cells and in glomerular mesangial regions.

Xiening Wu – 1 July 1987 – Gallstones, which were diagnosed in 365 patients on the basis of symptoms, signs, ultrasound scanning and cholecystography were treated by compression of specific auricular points. The patients were predominantly women (76%) from 19 to 78 years of age. The stones were in the gallbladder in 326, in intrahepatic ducts in 20, in the common bile duct in 6 and at multiple sites in 14.

Mary E. Charlson – 1 July 1987 – It has been suggested that gallbladder removal may protect against subsequent development of myocardial infarction because of increased gastrointestinal cholesterol excretion resulting from increased enterohepatic cycling. To test this hypothesis, the authors used data from two large case‐control studies of myocardial infarction–‐one conducted in 1976–1979 in 155 US hospitals and one conducted in 1980–1983 in 78 US hospitals. First, 550 female myocardial infarction cases were compared to 1,658 controls.

Moreye Nusbaum – 1 July 1987

Julio Vorobioff, Eduardo Picabea, Roberto Villavicencio, Viviana Puccini, Oscar Rossi, Juan Bordato, Marcelo Audano – 1 July 1987 – Different and contradictory results concerning the use of propranolol in the treatment of portal hypertension have been reported. This study was designed to investigate the hemodynamic effects of short‐ and long‐term administration of propranolol in portal hypertensive patients.

Alvaro N. A. Monteiro, Radovan Borojevic – 1 July 1987 – Interactions of liver connective tissue cells, skin fibroblasts and smooth muscle cells with collagen gels in vitro were studied and compared.

Mark Doolittle, Roger Bohman, Andres Durstenfeld, Joseph Cascarano – 1 July 1987 – Our objective was to correlate biochemical or functional properties that could be measured by fluorescence to individual nonparenchymal cell types by the simultaneous detection of forward angle light scatter and fluorescence. Cells were released from liver following selective digestion of hepatocytes by Pronase perfusion. To fractionate the cells according to size, isolates were subjected to unit gravity sedimentation on a 1 to 5% sucrose gradient.

Ghanshyam Lohiya, Laura Nichols, Dennis Hsieh, Sunita Lohiya, Hoan Nguyen – 1 July 1987 – During three seasons, 36 samples of foods served to mentally retarded clients with a high incidence of hepatocellular carcinoma were analyzed for aflatoxin. Aflatoxin was not detected (less than 5 ppb) by thinlayer liquid chromatography in 35 food samples containing peanuts, corn, wheat or milk. One peanut butter sample contained 20 ppb aflatoxin. Aflatoxin content of these foods was at or below the level permitted by the Food and Drug Administration.