Edward S. Feldman, Bruce R. Bacon – 1 May 1989 – Both human porphyria cutanea tarda and experimental hexachlorobenzene‐induced porphyria are associated with hepatic injury and are potentiated by excess hepatic iron. The mechanisms whereby cellular injury occurs and the synergistic role of iron overload are unknown. In the present experiments, we studied hepatic mitochondrial function and lipid peroxidation in rats with hexachlorobenzene‐induced porphyria in which iron loading was achieved by dietary carbonyl iron supplementation.

Katherine S. Koch, Hyam L. Leffert – 1 May 1989 – Two individuals undergoing orthotopic hepatic transplantation received livers from donors who were on average 10 kg smaller than themselves based on recipient ideal body weight. As a result, the donor livers in these 2 cases were 29%‐59% smaller than would be expected had the donor liver and recipient been matched ideally.

Swan N. Thung – 1 May 1989

Sarah C. Kalser – 1 May 1989

1 May 1989

1 May 1989

Hey‐Chi Hsu, Tsung‐Teh Wu, Jin‐Chuan Sheu, Chieng‐Yen Wu, Tzyy‐Jen Chiou, Chu‐Shue Lee, Ding‐Shinn Chen – 1 May 1989 – Hepatitis B virus surface and core antigens (HBsAg, HBcAg) were examined in the resected primary hepatocellular carcinoma from 204 patients who had HBsAg in serum. Ninety patients had small (<5 cm) and 114 had large hepatocellular carcinoma (>5 cm).

Norman B. Javitt – 1 May 1989

Rudi Schmid, Steven Schenker – 1 May 1989

Shujiro Takase, Akira Takada, Minoru Yasuhara, Mikihiro Tsutsumi – 1 May 1989 – Hepatic aldehyde dehydrogenase isozyme activity was measured in 51 patients with various types of liver diseases, including 24 patients with alcoholic liver disease, to elucidate the relationship between hepatic aldehyde dehydrogenase activity and liver disease, especially alcoholic liver disease. The levels of low‐Km and total aldehyde dehydrogenase activity in the liver decreased both in alcoholic and nonalcoholic liver disease patients, who showed an isoelectric focusing pattern of the usual type.