J. P. Colombo – 1 March 1987 – Portacaval shunt (PCS) operations were performed on male inbred SD rats. The activity of liver γ‐glutamyltranspeptidase (GGT) increased a few days after the operation and remained high after several months. However, the activity was only present in periportal areas of liver lobules and was mainly restricted to the endothelial lining cells of periportal blood vessels. Phenobarbital sodium (CAS: 57–03–7) administration did not change the distribution of GGT.

Keith S. Henley – 1 March 1987

Robert L. Carithers – 1 March 1987

B. A. Runyon – 1 March 1987

Syoji Kuroki, Erwin H. Mosbach, Richard J. Stenger, Bertram I. Cohen, Charles K. McSherry – 1 March 1987 – The metabolism and effect on biliary lipids of a new bile acid analog, 7‐methyl‐deoxycholic acid, were studied and compared with those of deoxycholic acid in the hamster. 14C‐Labeled 7‐methyl‐deoxycholic acid and deoxycholic acid were administered intravenously or intraduodenally to bile fistula hamsters at 1.0 or 4.0 μmoles per min·kg, and hepatic bile was analyzed for radioactive metabolites and biliary lipid outputs.

David G. Oelberg, William P. Dubinsky, Jeffrey W. Sackman, Leslie B. Wang, Eugene W. Adcock, Roger Lester – 1 March 1987 – At high concentrations, bile salts induce hemolysis by comicellization of lipid components of the cell membrane. However, bile salts are also associated with hemolysis at lower concentrations by mechanisms which have not been characterized.

Toshikazu Uchida, Koyu Suzuki, Mariko Esumi, Masayuki Arii, Masashi Oomura, Toshio Shikata – 1 January 1987 – A sequential study was performed to investigate the occurrence and localization of duck hepatitis B virus in the liver of domestic ducks utilizing the indirect immunoperoxidase method and electron microscopy. Seventeen ducklings were injected intravenously with duck hepatitis B virus‐positive serum within 24 hr after hatching and were subsequently sacrificed on the 2nd, 3rd, 4th, 5th, 27th and 44th day after injection.

Tzee Chung Wu, Myron J. Tong, Betau Hwang, Shou‐Dong Lee, Mu Mei Hu – 1 January 1987 – Twenty pediatric patients with primary hepatocellular carcinoma in Taiwan were tested for HBsAg, and all were found to be positive. The youngest case was 8 months of age, five cases occurred between 9 and 10 years of age, and 14 cases occurred between 11 and 16 years of age. The serum α‐fetoprotein was elevated in all 20 primary hepatocellular carcinoma patients, and the average survival of these cases after diagnosis was 4.7 months.

Laurence M. Blendis, Michael J. Sole, Peter Campbell, Alan G. Lossing, Paul D. Greig, Bryce R. Taylor, Bernard Langer – 1 January 1987 – The elevated catecholamine levels in cirrhotic patients with ascites have been proposed to be due to sympathetic overactivity secondary either to reduced intravascular volume or to an underlying cardiovascular abnormality such as reduced pressor responsiveness. Furthermore, these elevated catecholamine levels have been proposed to be involved in the pathogenesis of salt and water retention.

James E. Heubi, John C. Partin, Jacqueline S. Partin, William K. Schubert – 1 January 1987