How proteins move across the endoplasmic reticulum membrane
Günter Blobel – 1 January 1987
Reactivities and clinical relevance of antimitochondrial antibodies to four mitochondrial inner membrane proteins in sera of patients with primary biliary cirrhosis
Hideo Ishii, Koji Saifuku, Toshihiko Namihisa – 1 January 1987 – Antimitochondrial antibodies are characteristically detected in sera of patients with primary biliary cirrhosis. The antigens to which the antimitochondrial antibodies in primary biliary cirrhosis sera react have been located in the mitochondrial inner membrane. We have reported on four mitochondrial inner membrane proteins, extracted from beef heart, which reacted with antimitochondrial antibodies of primary biliary cirrhosis. These four proteins had molecular weights of 70, 54, 51 and 45 kd.
Opsonins in the hepatic clearance of pneumococci
B. A. Runyon – 1 January 1987 – An in situ isolated, perfused rat liver system was used to evaluate various opsonins for hepatic trapping and killing of encapsulated, virulent, type 3 pneumococci. Pneumococci were rapidly trapped in the liver in the presence of all potential opsonins including Hanks balanced salt solution with added colloid. However, with some of the potential opsonins the organisms remained viable and could be recovered from the liver. With others there was killing of pneumococci.
Masthead
1 January 1987
Liver‐specific gene expression in various pathophysiologic states
Arturo Panduro, Fouad Shalaby, David A. Shafritz – 1 January 1987
Development of molecular hybridization technology to evaluate albumin and procollagen mrna content in baboons and man
Francis R. Weiner, Mark J. Czaja, Marie‐Adele Giambrone, Catherine H. Wu, George Y. Wu, Mark A. Zern – 1 January 1987 – We have developed the methodology for evaluating the effects of pathophysiological conditions on the molecular mechanisms of hepatic protein synthesis and fibrogenesis in baboons and man. Total RNA was extracted from percutaneous liver biopsies of five baboons who were chronically fed an ethanol‐rich liquid diet, their pair‐fed controls and from humans with a variety of liver abnormalities.
The structure of the human apolipoprotein genes
Lawrence Chan – 1 January 1987
Structure and expression of the hepatitis B virus genome
Marie‐Louise Michel, Pierre Tiollais – 1 January 1987
Molecular aspects of persistent woodchuck hepatitis virus and hepatitis B virus infection and hepatocellular carcinoma
Charles E. Rogler, Okio Hino, Chun‐Yeh Su – 1 January 1987
The effect of changes in the fluid state of rat liver plasma membrane on the transport of taurocholate
Peter R. Mills, Peter J. Meier, Daniel J. Smith, Nazzareno Ballatori, James L. Boyer, Ellen R. Gordon – 1 January 1987 – The fluidity of basolateral and canalicular rat liver plasma membranes was compared with respect to their response to the membrane perturbants ethanol and calcium. The relation between membrane fluidity and taurocholate transport, a liver plasma membrane function mediated by carrier proteins, was also examined. Membrane fluidity was measured by fluorescence polarization using 1,6‐diphenyl‐1,3,5‐hexatriene as a probe.