B. A. Runyon – 1 March 1987

Syoji Kuroki, Erwin H. Mosbach, Richard J. Stenger, Bertram I. Cohen, Charles K. McSherry – 1 March 1987 – The metabolism and effect on biliary lipids of a new bile acid analog, 7‐methyl‐deoxycholic acid, were studied and compared with those of deoxycholic acid in the hamster. 14C‐Labeled 7‐methyl‐deoxycholic acid and deoxycholic acid were administered intravenously or intraduodenally to bile fistula hamsters at 1.0 or 4.0 μmoles per min·kg, and hepatic bile was analyzed for radioactive metabolites and biliary lipid outputs.

David G. Oelberg, William P. Dubinsky, Jeffrey W. Sackman, Leslie B. Wang, Eugene W. Adcock, Roger Lester – 1 March 1987 – At high concentrations, bile salts induce hemolysis by comicellization of lipid components of the cell membrane. However, bile salts are also associated with hemolysis at lower concentrations by mechanisms which have not been characterized.

Toshikazu Uchida, Koyu Suzuki, Mariko Esumi, Masayuki Arii, Masashi Oomura, Toshio Shikata – 1 January 1987 – A sequential study was performed to investigate the occurrence and localization of duck hepatitis B virus in the liver of domestic ducks utilizing the indirect immunoperoxidase method and electron microscopy. Seventeen ducklings were injected intravenously with duck hepatitis B virus‐positive serum within 24 hr after hatching and were subsequently sacrificed on the 2nd, 3rd, 4th, 5th, 27th and 44th day after injection.

Tzee Chung Wu, Myron J. Tong, Betau Hwang, Shou‐Dong Lee, Mu Mei Hu – 1 January 1987 – Twenty pediatric patients with primary hepatocellular carcinoma in Taiwan were tested for HBsAg, and all were found to be positive. The youngest case was 8 months of age, five cases occurred between 9 and 10 years of age, and 14 cases occurred between 11 and 16 years of age. The serum α‐fetoprotein was elevated in all 20 primary hepatocellular carcinoma patients, and the average survival of these cases after diagnosis was 4.7 months.

Laurence M. Blendis, Michael J. Sole, Peter Campbell, Alan G. Lossing, Paul D. Greig, Bryce R. Taylor, Bernard Langer – 1 January 1987 – The elevated catecholamine levels in cirrhotic patients with ascites have been proposed to be due to sympathetic overactivity secondary either to reduced intravascular volume or to an underlying cardiovascular abnormality such as reduced pressor responsiveness. Furthermore, these elevated catecholamine levels have been proposed to be involved in the pathogenesis of salt and water retention.

James E. Heubi, John C. Partin, Jacqueline S. Partin, William K. Schubert – 1 January 1987

Paul D. Berk, Barry J. Potter, Wolfgang Stremmel – 1 January 1987

Jan Van Hattum, Geziena M. Th. Schreuder, Solko W. Schalm – 1 January 1987 – The course after hepatitis B virus infection seems to be determined by the host's immune response, which in turn may be regulated by the major histocompatibility complex. In order to find a possible relationship between the course of disease and the phenotype frequency of HLA determinants, we studied 396 Dutch subjects of northern European local race. Six groups of individuals with various courses after hepatitis B virus infection were compared to healthy controls.

Atsushi Kanno, Hitoshi Ohori, Keizaburoh Matsuda, Haruo Nakayama, Yutaka Miyazaki, Motoyasu Ishii, Hiroshi Suzuki, Masao Ohtsuki, Yoshio Goto – 1 January 1987 – In order to establish the virological significance of HBeAg subtypes (HBeAg/1 and HBeAg/2) during hepatitis B virus infection, HBsAg, HBeAg and hepatitis B virus DNA in serum and HBeAg in liver were determined quantitatively in relation to the detection of HBeAg subtypes in agar gel diffusion.