Vivek Dixit, Ruth Darvasi, Marika Arthur, Maria Brezina, Klaus Lewin, Gary Gitnick – 1 December 1990 – Microencapsulation of cells within synthetic semipermeable membranes is a novel technique that enables the transplantation of cell cultures without the need for immunosuppression. We have previously shown that transplanted isolated encapsulated hepatocytes can provide sufficient short‐term metabolic support to improve the survival of animals with galactosamine‐induced fulminant hepatic failure.

Charles S. Lieber, Leonore M. Decarli, Ki M. Mak, Cho‐Il Kim, Maria A. Leo – 1 December 1990 – Characteristic features of alcoholic liver injury include fibrosis and striking membrane alterations, with associated phospholipid changes. To offset some of these abnormalities, a 10‐yr study was conducted in baboons: 12 animals (eight females, four males) were fed a liquid diet supplemented with polyunsaturated lecithin (4.1 mg/kcal) for up to 8 yr, with either ethanol (50% of total energy) or isocaloric carbohydrate.

Harold O. Conn, Marilyn B. Conn – 1 December 1990

Robert P. Perrillo – 1 December 1990

Gloria Moraleda, Javier Bartolomé, Maria Gracia Martinez, Juan Carlos Porres, Vicente Carreño – 1 December 1990 – The presence of hepatitis B virus DNA was studied in peripheral blood mononuclear cell samples from 259 HBsAg carriers (229 anti‐hepatitis delta negative, 30 anti‐hepatitis delta positive), 16 anti‐HBc—positive HBsAg‐negative patients and 30 patients without hepatitis B virus markers.

Claire Guyomard, Christophe Chesne, Bernard Meunier, Alain Fautrel, Catherine Clerc, Fabrice Morel, Maryvonne Rissel, Jean‐Pierre Campion, André Guillouzo – 1 December 1990 – Rat livers were perfused and stored for 48 hr in cold University of Wisconsin solution before dissociation by the two‐step collagenase method. At that time, glycogen content was significantly reduced, but no obvious changes in albumin, β‐actin and aldolase B mRNAs and in glutathione levels were observed. Enzymatic perfusion yielded 280 ± 30 × 106 viable hepatocytes vs.

Steven Schenker, S. Angela Khan – 1 December 1990

Fredric Regenstein – 1 December 1990

Hector Orrego, Laurence M. Blendis, Yedy Israel – 1 December 1990

1 December 1990