Helmut K. Seitz, Bernhard Kuhn, Eberhard von Hodenberg, Walter Fiehn, Christian Conradt, Ulrich A.
Leonardo Bianchi, Jürg Reichen – 1 August 1994
Sum P. Lee, Alex Hayashi, Young S. Kim – 1 August 1994
Agostino Colli, Massimo Cocciolo, David Sacerdoti, Massimo Bolognesi, Carlo Merkel, Paolo Angeli, Angelo Gatta – 1 August 1994
1 August 1994
Joel F. Platt, James H. Ellis, Jonathan M. Rubin, Robert M. Merion, Michael R. Lucey – 1 August 1994 – Hepatorenal failure, a well‐recognized complication of established liver disease, is characterized by early renal hemodynamic changes (vasoconstriction) before clinically recognized kidney disease. This renal vasoconstruction (increased renal vascular resistance) should be detectable noninvasively by Doppler ultrasonography.
Ronald J. Sokol – 1 August 1994 – The LEC rat is an inbred mutant strain with spontaneous hepatitis isolated from Long‐Evans rats. Since approximately 40% of LEC rats die of fulminant hepatitis, the rat serves an animal model for studying the pathogenesis and treatment of human fulminant hepatitis. The remaining 60% of LEC rats survive and develop chronic (prolonged) hepatitis and subsequently develop liver cancer.
John Hansen, David L. Cherwitz, John I. Allen – 1 August 1994 – An in vivo model of ethanol ingestion in rats was used to examine tumor necrosis factor‐α production after intravenous injection with lipopolysaccharide or saline solution. Four groups of 125‐gm male Sprague‐Dawley rats were given one of the following four diets: liquid ethanol diet (ethanol, 36% of calories), liquid control diet, chow ad libitum or control liquid diet pair‐fed to match calories consumed by ethanol‐fed rats. After 6 wk of diet, all rats were injected with 1 mg/kg lipopolysaccharide or 0.9% saline.
Anthony S. Basile, E. Anthony Jones, Peter Widler, Hans U. Fisch, Thomas Schläepfer, Jürg Reichen, Peter Schoch – 1 August 1994
Frank J. Farrell, Marie Nguyen, Susan Woodley, Joanne C. Imperial, Richard Garcia‐Kennedy, Kevin Man, Carlos O. Esquivel, Emmet B. Keeffe – 1 August 1994 – Recent preliminary reports suggest a poor outcome of orthotopic liver transplantation for patients with hemochromatosis. We analyzed an institutional experience with orthotopic liver transplantation for hemochromatosis, focusing on factors contributing to increased morbidity and mortality. Between March 1988 and October 1992, nine of 249 adults (3.6%) undergoing orthotopic liver transplantation had hemochromatosis.