Ronald J. Sokol – 1 August 1994 – The LEC rat is an inbred mutant strain with spontaneous hepatitis isolated from Long‐Evans rats. Since approximately 40% of LEC rats die of fulminant hepatitis, the rat serves an animal model for studying the pathogenesis and treatment of human fulminant hepatitis. The remaining 60% of LEC rats survive and develop chronic (prolonged) hepatitis and subsequently develop liver cancer.
Joel F. Platt, James H. Ellis, Jonathan M. Rubin, Robert M. Merion, Michael R. Lucey – 1 August 1994 – Hepatorenal failure, a well‐recognized complication of established liver disease, is characterized by early renal hemodynamic changes (vasoconstriction) before clinically recognized kidney disease. This renal vasoconstruction (increased renal vascular resistance) should be detectable noninvasively by Doppler ultrasonography.
1 August 1994
Agostino Colli, Massimo Cocciolo, David Sacerdoti, Massimo Bolognesi, Carlo Merkel, Paolo Angeli, Angelo Gatta – 1 August 1994
Sum P. Lee, Alex Hayashi, Young S. Kim – 1 August 1994
Leonardo Bianchi, Jürg Reichen – 1 August 1994
Helmut K. Seitz, Bernhard Kuhn, Eberhard von Hodenberg, Walter Fiehn, Christian Conradt, Ulrich A.
Minoru Tomita, Kazuhide Yamamoto, Haruhiko Kobashi, Masaki Ohmoto, Takao Tsuji – 1 August 1994 – The phenotypical heterogeneity of human liver macrophages was analyzed with monoclonal antibodies that recognize antigens specific for the monocytemacrophage lineage. Most liver macrophages in normal and diseased liver were positive for CD68, whereas fewer matured macrophages were detected by 25–F9. Comparative staining of mirror sections revealed some to be doubly positive and others to be singly CD68 positive.
Raymond S. Koff – 1 August 1994