Renal duplex doppler ultrasonography: A noninvasive predictor of kidney dysfunction and hepatorenal failure in liver disease

Joel F. Platt, James H. Ellis, Jonathan M. Rubin, Robert M. Merion, Michael R. Lucey – 1 August 1994 – Hepatorenal failure, a well‐recognized complication of established liver disease, is characterized by early renal hemodynamic changes (vasoconstriction) before clinically recognized kidney disease. This renal vasoconstruction (increased renal vascular resistance) should be detectable noninvasively by Doppler ultrasonography.

Immunohistochemical phenotyping of liver macrophages in normal and diseased human liver

Minoru Tomita, Kazuhide Yamamoto, Haruhiko Kobashi, Masaki Ohmoto, Takao Tsuji – 1 August 1994 – The phenotypical heterogeneity of human liver macrophages was analyzed with monoclonal antibodies that recognize antigens specific for the monocytemacrophage lineage. Most liver macrophages in normal and diseased liver were positive for CD68, whereas fewer matured macrophages were detected by 25–F9. Comparative staining of mirror sections revealed some to be doubly positive and others to be singly CD68 positive.

Profiles of expression of carbohydrate chain structures during human intrahepatic bile duct development and maturation: A lectin‐histochemical and immunohistochemical study

Tadashi Terada, Yasuni Nakanuma – 1 August 1994 – We investigated expression of carbohydrate chain structures during human intrahepatic bile duct development and maturation. Results of staining for ABH antigens were negative in the ductal plate and biliary cells migrating into the mesenchyma but were positive in newly formed bile ducts in the fetal liver and in maturing bile ducts in the postnatal liver. Staining for Lewisa, sialyl Lewisa and Lewisb antigens was negative in the ductal plate but positive in migrating biliary cells, newly formed ducts and maturing ducts.

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