Immunoglobulins and α1‐acid glycoprotein do not contribute to the cholesterol crystallization—promoting effect of concanavalin a—binding biliary protein
Marianne A. C., De Bruijn, Kam S. Mok, Tiny Out, Guido N. J. Tytgat, Albert K. Groen – 1 September 1994 – Human bile contains cholesterol crystallization—stimulating proteins that can be isolated by concanavalin A—Sepharose chromatography. In the past few years an increasing number of different pronucleating proteins have been identified in the concanavalin A—binding fraction. In this study we attempted to estimate the relative contribution of a number of these proteins to total concanavalin A—binding pronucleating activity.
Papaverine inhibits bile acid excretion in isolated perfused rat liver
Tomoyuki Kumai, Makoto Hoshino, Tomihiro Hayakawa, Katsuyoshi Higashi – 1 September 1994 – We investigated the effects of papaverine on bile acid excretion into bile in the presence of infusions of taurocholic acid, tauroursodeoxycholic acid, taurochenodeoxycholic acid and taurodehydrocholic acid in a single‐pass, isolated perfused rat liver model.
Cell adhesion molecules in human organ transplants. By G. Steinhoff, 110 pp. Austin: R.G. Landes, 1993. $89.95
Raymond S. Koff – 1 September 1994
Notices
1 September 1994
Posttranslational events involved in griseofulvin‐induced keratin cytoskeleton alterations
Hermann Salmhofer, Ingrid Rainer, Kurt Zatloukal, Helmut Denk – 1 September 1994 – Alcoholic hepatitis is a disease associated with profound alterations of the hepatocytic intermediate filament cytoskeleton. Similar cytoskeletal alterations can be induced in mice with prolonged feeding of the fungistatic drug griseofulvin. Murine hepatocytic intermediate filaments are composed of equimolar amounts of keratin polypeptides A (type II) and D (type I).
The role of inflammatory mediators on hepatitis B virus surface expression in a transgenic mouse model
1 September 1994 – We have recently reported that administration of recombinant tumor necrosis factor‐alpha to hepatitis B virus transgenic mice reduces the hepatic steadystate content of HBV‐specific mRNA by up to 80% in the absence of liver cell injury. In the current study, we analyzed the regulatory effects of several other inflammatory cytokines in the same transgenic model system. Hepatic HBV mRNA content was reduced by up to 90% following administration of a single noncytopathic dose (100,000U) of interleukin‐2.
Correction
1 September 1994
Impact of shunt surgery for variceal bleeding in the natural history of ascites in cirrhosis: A retrospective study
Antoni Castells, Joan Saló, Ramon Planas, Juan Carlos Quer, Angels Ginès, Jaume Boix, Pere Ginès, Miquel Angel Gassull, Josep Terés, Vicente Arroyo, Joan Rodés – 1 September 1994 – Despite the efficacy of shunt surgery in the treatment of variceal bleeding, less effective nonoperative therapies are being substituted because surgical shunt does not modify survival and increases hepatic encephalopathy. However, the real impact of shunt surgery on the natural history of ascites and its complications has not been established.