Notices
1 September 1994
Cell adhesion molecules in human organ transplants. By G. Steinhoff, 110 pp. Austin: R.G. Landes, 1993. $89.95
Raymond S. Koff – 1 September 1994
Papaverine inhibits bile acid excretion in isolated perfused rat liver
Tomoyuki Kumai, Makoto Hoshino, Tomihiro Hayakawa, Katsuyoshi Higashi – 1 September 1994 – We investigated the effects of papaverine on bile acid excretion into bile in the presence of infusions of taurocholic acid, tauroursodeoxycholic acid, taurochenodeoxycholic acid and taurodehydrocholic acid in a single‐pass, isolated perfused rat liver model.
Immunoglobulins and α1‐acid glycoprotein do not contribute to the cholesterol crystallization—promoting effect of concanavalin a—binding biliary protein
Marianne A. C., De Bruijn, Kam S. Mok, Tiny Out, Guido N. J. Tytgat, Albert K. Groen – 1 September 1994 – Human bile contains cholesterol crystallization—stimulating proteins that can be isolated by concanavalin A—Sepharose chromatography. In the past few years an increasing number of different pronucleating proteins have been identified in the concanavalin A—binding fraction. In this study we attempted to estimate the relative contribution of a number of these proteins to total concanavalin A—binding pronucleating activity.
Hepatology Elsewhere correspondence. Hepatocellular carcinoma and viral cirrhosis
Paolo Gentilini, Lorenzo Melani, Donato Riccardi, Vincenzo Casini Raggi, Roberto G. Romanelli – 1 September 1994
The eosinophil as an effector cell of the immune response during hepatic allograft rejection
Piet C. De Groen, Gail M. Kephart, Gerald J. Gleich, Jurgen Ludwig – 1 September 1994 – Objective: To evaluate the role of the eosinophil granulocyte during hepatic allograft rejection. Design: (a) A retrospective case‐control study and (b) a prospective study of consecutive liver transplant recipients. Patients: In the retrospective study, eight patients with severe rejection in the first month after liver transplantation were compared with six patients without rejection.
Hepatitis C virus: From epidemiology and molecular virology to immunobiology
Johnson Y. N. Lau – 1 September 1994 – Hepatitis C virus (HCV) is a major cause of posttransfusion and community‐acquired hepatitis, and a majority of individuals infected with this virus will subsequently develop chronic hepatitis. Characterization of the host immune response to this infection is an important first step that should facilitate the development of immunomodulatory agents and vaccines. Cellular immune responses, especially those mediated by cytotoxic T lymphocytes (CTL), are important in the control of many viral diseases.
Changes in distribution and activity of glutamine synthetase in carbon tetrachloride‐induced cirrhosis in the rat: Potential role in hyperammonemia
Rolf Gebhardt, Jürg Reichen – 1 September 1994 – Cirrhosis induced in rats by carbon tetrachloride was used to study alterations in the activities and lobular distribution of carbamoylphosphate synthetase and glutamine synthetase. Specific activity of carbamoylphosphate synthetase in cirrhotic subjects was decreased to 70% of controls. Staining was homogeneous within micronodular areas, but varied from area to area and generally showed a decreased intensity.