Effect of a Multistrain Probiotic on Cognitive Function and Risk of Falls in Patients With Cirrhosis: A Randomized Trial

Eva Román, Juan Camilo Nieto, Cristina Gely, Sílvia Vidal, Marta Pozuelo, Maria Poca, Cándido Juárez, Carlos Guarner, Chaysavanh Manichanh, Germán Soriano – 12 March 2019 – Probiotics can modulate gut microbiota, intestinal permeability, and immune response and could therefore improve cognitive dysfunction and help avoid potential consequences, such as falls, in patients with cirrhosis. The aim of this study was to evaluate the effect of a multistrain probiotic on cognitive function, risk of falls, and inflammatory response in patients with cirrhosis.

Collagen Formation Assessed by N‐Terminal Propeptide of Type 3 Procollagen Is a Heritable Trait and Is Associated With Liver Fibrosis Assessed by Magnetic Resonance Elastography

Cyrielle Caussy, Meera Bhargava, Ida F. Villesen, Natasja S. Gudmann, Diana J. Leeming, Morten A. Karsdal, Claire Faulkner, Denny Bao, Amy Liu, Min‐Tzu Lo, Ricki Bettencourt, Shirin Bassirian, Lisa Richards, David A. Brenner, Chi‐Hua Chen, Claude B. Sirlin, Rohit Loomba – 12 March 2019 – N‐terminal propeptide of type 3 procollagen (PRO‐C3) is a biomarker of liver fibrosis in nonalcoholic fatty liver disease (NAFLD).

Home‐Based Exercise in Patients Awaiting Liver Transplantation: A Feasibility Study

Felicity Rhian Williams, Alice Vallance, Thomas Faulkner, Jennifer Towey, Simon Durman, Derek Kyte, Ahmed Mohamed Elsharkawy, Thamara Perera, Andrew Holt, James Ferguson, Janet M. Lord, Matthew James Armstrong – 11 March 2019 – Frailty is associated with increased mortality both before and after liver transplantation (LT). There are no standardized exercise programs, in particular home‐based exercise programs (HBEPs), for patients awaiting LT. The aim was to investigate the feasibility of such a program in patients awaiting LT.

Genome‐wide Association Studies of Specific Antinuclear Autoantibody Subphenotypes in Primary Biliary Cholangitis

Chan Wang, Xiaodong Zheng, Peng Jiang, Ruqi Tang, Yuhua Gong, Yaping Dai, Lan Wang, Ping Xu, Wenjuan Sun, Lu Wang, Chongxu Han, Yuzhang Jiang, Yiran Wei, Kui Zhang, Jian Wu, Youlin Shao, Yueqiu Gao, Jianjiang Yu, Zhigang Hu, Zhidong Zang, Yi Zhao, Xudong Wu, Na Dai, Lei Liu, Jinshan Nie, Bo Jiang, Maosong Lin, Li Li, You Li, Sufang Chen, Lixin Shu, Fang Qiu, Qiuyuan Wu, Mingming Zhang, Ru Chen, Rohil Jawed, Yu Zhang, Xingjuan Shi, Zhen Zhu, Hao Pei, Lihua Huang, Weifeng Zhao, Ye Tian, Xiang Zhu, Hong Qiu, M. Eric Gershwin, Weichang Chen, Michael F.

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