Randomized Trial of Spheroid Reservoir Bioartificial Liver in Porcine Model of Posthepatectomy Liver Failure
Harvey S. Chen, Dong Jin Joo, Mohammed Shaheen, Yi Li, Yujia Wang, Jian Yang, Clara T. Nicolas, Kelly Predmore, Bruce Amiot, Gregory Michalak, Taofic Mounajjed, Jeff Fidler, Walter K. Kremers, Scott L. Nyberg – 19 July 2018 – Acute liver failure (ALF) is a catastrophic condition that can occur after major liver resection. The aim of this study was to determine the effects of the spheroid reservoir bio‐artificial liver (SRBAL) on survival, serum chemistry, and liver regeneration in posthepatectomy ALF pigs.