Naoto Aoki, Michael A. Gerber, Swan N. Thung, Mei‐Ling Chen, Judith K. Christman, Peter M. Price, Christos S. Flordellis, George Acs – 1 January 1984 – Cultured 3T3 mouse fibroblasts transfected with cloned hepatitis B virus genome and DNA coding for methotrexate‐resistant dihydrofolate reductase, produce and secrete significant amounts of hepatitis B surface antigen (HBsAg).
Irwin H. Rosenberg – 1 January 1984
Charles S. Davidson, Raymond S. Koff – 1 January 1984
Steven Schenker – 1 January 1984
Steven Schenker – 1 January 1984
David Schachter – 1 January 1984
Bruce F. Scharschmidt – 1 January 1984 – The results of liver transplantation in a total of 540 patients from four centers in the United States and Western Europe have been collated. Twenty‐five per cent of all transplants were performed for neoplastic disease. One– and 3–year survivals for this group were approximately 26 and 12% overall, and survival differed little for patients transplanted before and after January 1, 1980. Among the 44% of patients transplanted for endstage cirrhosis, 3–year survival was lowest for patients with alcoholic cirrhosis (20%).
Jean‐Claude Barbare, Raoul Poupon, Patrice Jaillon, Philippe Bories, Michele Aussanaire, François Darnis, Henri Michel, Georges Cheymol – 1 January 1984 – We studied the influence of posterior pituitary extract, vasopressin, and somatostatin on hepatic elimination function. Hepatic clearance and its two biological determinants, hepatic blood flow and metabolic activity (clearance Vmax/Km), were determined from hepatic indocyanine green elimination at steady‐state in cirrhotic patients.
Adolf Stiehl, Richard Raedsch, Gerda Rudolph, Siegfried Walker – 1 January 1984 – In five patients with radiolucent gallstones, the effect of ursodeoxycholic acid (Urso) in doses of 250, 500, 750, 1,000, and 1,250 mg per day on biliary lipid and bile acid composition was studied. Biliary cholesterol decreased from 8.8 ± 0.8 mole% to 4.4 ± 0.2 mole% at 500 mg Urso per day (7.1 mg per kg) and to 4.2 ± 0.3 mole% at 750 mg Urso per day (10.7 mg per kg). Administration of 1,000 or 1,250 mg Urso per day produced no further decrease of biliary cholesterol.
Dale C. Snover, Sally A. Weisdorf, Norma K. Ramsay, Philip Mcglave, John H. Kersey – 1 January 1984 – Ninety‐six liver biopsies [32 bone marrow transplant (BMT), 7 pre‐BMT, and 57 non‐BMT] are reviewed for histological evidence of graft versus host disease (GVHD), based on bile duct atypia and related inflammatory changes. In addition, the presence of cholestasis, piecemeal necrosis, and attachment of lymphocytes to vascular endothelium (endothelialitis) are evaluated.