The Effect of Bile Duct Obstruction on the Clearance of Circulating IgA Immune Complexes
Paul R. Harmatz, Ronald E. Kleinman, Bruce W. Bunnell, Daniel T. Mcclenathan, W. Allan Walker, Kurt J. Bloch – 1 January 1984 – The clearance of circulating IgA immune complexes following acute bile duct obstruction was investigated in this study. IgA immune complexes were formed in vitro from MOPC‐315, an IgA M‐component with anti‐dinitrophenyl (DNP) specificity, and 125I‐DNP10 bovine serum albumin (BSA). Eighteen hours after laparotomy during which the common bile duct was either identified only or identified and ligated, the IgA immune complexes were injected intravenously.