Mark I. Avigan, Kamal G. Ishak, Richard E. Gregg, Jay H. Hoofnagle – 1 November 1984 – Liver tissue of a newly diagnosed 30‐year‐old patient with abetalipoproteinemia was studied by light and electron microscopy. Despite accumulation of large quantities of lipid droplets in hepatocytes, the lobular architecture remained intact, and there was no fibrosis. Acanthocytes were readily identified in sinusoids by scanning electron microscopy. Profiles of rough endoplasmic reticulum, smooth endoplasmic reticulum and Golgi apparatus appeared normal by transmission electron microscopy.

William V. Mcdermott – 1 November 1984

1 November 1984

Rachel Morecki, Joy H. Glaser, Anne B. Johnson, Yvonne Kress – 1 November 1984 – This report describes immunocytochemical and ultrastructural methods which led to the identification of Reovirus type 3 (Reo‐3) in the porta hepatis of a patient with extrahepatic biliary atresia. The study indicates that Reo‐3 antigenic sites are demonstrable by the avidin‐biotinylated complex peroxidase method following formalin fixation and paraffin embedding, but are destroyed by freezing and thawing prior to fixation.

Bruce A. Runyon, John C. Hoefs – 1 November 1984 – A review of the medical records of patients diagnosed as having “spontaneous bacterial peritonitis” (SBP) revealed 18 episodes of culture‐negative neutrocytic ascites (CNNA) in 17 patients. The following criteria were all required in order to qualify for this diagnosis: (i) an ascitic fluid neutrophil count greater than 500 cells per mm3; (ii) negative ascitic fluid culture (5); (iii) absence of an intraabdominal source of infection; (iv) no antibiotic treatment within 30 days, and (v) no evidence of pancreatitis.

1 November 1984

Christine M. Cornely, Robert R. Schade, David H. Van Thiel, Judith S. Gavaler – 1 November 1984 – The prevalence of impotence is increased in males who chronically abuse alcohol. Further, impotence may occur in the absence of liver disease in such men. In contrast, no data is available concerning the prevalence of impotence in nonalcoholic men with advanced liver disease.

Edna Ben‐Porath, Jack Wands, Mignon Gruia, Kurt Isselbacher – 1 November 1984 – We assessed the significance of the enhanced detection by monoclonal radioimmunoassay (M‐RIA) of HBsAg in serum of patients with hepatitis B virus (HBV) infection. In acute HBV infection, the M‐RIA detected HBsAg in the blood for a far longer period of time than previously recognized. In some patients, the “window phase” of HBV infection (defined as the presence of anti‐HBc and the lack of detectable HBsAg and anti‐HBs) was shortened or completely eliminated.

Roger Lester – 1 November 1984

Junko Mori, Masao Omata, Osamu Yokosuka, Fumio Imazeki, Yoshimi Ito, Katsuo Uchiumi, Yasuhisa Matsuyama, Ye Weifa, Kunio Okuda – 1 November 1984 – Liver sections were stained with orcein, and duck hepatitis B virus was identified in sera and livers by the hybridization technique in 106 ducks (44 Chinese ducks, 15 Japanese ducks and 47 Japanese ducklings). Orcein‐positive hepatocytes were found in 18 of 38 (47%) duck hepatitis B virus DNA seropositive ducks, and only in 3 of 68 (4%) seronegative ducks. The three ducks were all from a heavily infected flock in southern China.