Hemodynamic study during transdermal application of nitroglycerin tape in patients with cirrhosis
Tadashi Iwao, Atsushi Toyonaga, Michihiro Sumino, Kohsuke Takagi, Kazunori Ohkubo, Rintaroh Inoue, Kyuichi Tanikawa – 1 January 1991 – We studied 14 patients with portal hypertension and cirrhosis using portal and hepatic vein catheterizations to determine the effects of transdermal application of nitroglycerin tape (containing 10 mg of nitroglycerin and capable of releasing 6 to 7 mg of nitroglycerin in 12 hr) on splanchnic hemodynamics. Patients randomly received nitroglycerin (n = 7) or a placebo (n = 7). No significant changes were observed after the administration of the placebo.