Antimicrosomal antibodies: What are they telling us?
Paul B. Watkins – 1 February 1991 – Patients with dihydralazine hepatotoxicity have been found to have circulating autoantibodies that react with liver microsomes (anti‐liver microsome antibodies) and that are clearly distinct from anti‐liver and kidney microsomal antibodies observed in patients with tienilic acid‐induced hepatitis and in some patients with autoimmune hepatitis. The authors show that anti‐liver microsome antibodies present in the sera of five patients with dihydralazine‐induced hepatitis specifically react on immunoblots with a 53 kD protein.