B. Emmanuel Akinshola, James J. Potter, Esteban Mezey – 1 March 1991 – The acute effects of ethanol on total (bound + free) pyridine dinucleotides were determined in freshly isolated rat hepatocytes. Pyridine dinucleotides and adenine nucleotides were determined by highperformance liquid chromatography. Exposure of the hepatocytes to 8 mmol/L ethanol resulted in a decrease in NAD+ and an increase in NADP+ after 2 min incubation. There were no significant changes in NADH and NADPH.

Gary A. Clawson, Kenneth R. Madsen, Lori J. Blankenship, Christine L. Hatem – 1 March 1991 – Liver regeneration was induced in rats by treatment with CCl4, which results in substantial regenerative activity with a sharp mitotic response 2 days after intoxication. Closely paralleling the mitotic index, we observed fourfold increases in nuclear scaffold nucleoside triphosphatase, an activity thought to participate in nucleocytoplasmic RNA transport and in the 46 kD putative enzyme and its selective photolabeling.

Jorge J. Gumucio, Donald L. Kaminski – 1 March 1991

Jorge J. Gumucio, Frank C. Powell, Roy S. Rogers, E. Rolland Dickson – 1 March 1991 – Objective – To assess the association of lichen planus with liver complaints and with known etiological factors of liver diseases.

Tai‐Wing Wu, Noriaki Hashimoto, Jian‐Xun Au, Jun Wu, Donald A. G. Mickle, Doug Carey – 1 March 1991 – Trolox, a hydrophilic analog of vitamin E, was reported to scavenge peroxyl radicals from artificial systems better than its parent compound. Here we examined the possible cytoprotective effect of Trolox in cultured hepatocytes and in the rat liver.

Leo T. McCallum – 1 March 1991

Emanuel Sikuler, Are Moran, J. Michael Henderson, Hussein M. Atta, G. Thomas Gilmore – 1 March 1991

Denis Vetter, Jean‐Jacques Wenger, Jean‐Michel Bergier, Michel Doffoel, René Bockel – 1 March 1991 – Transcatheter oily chemoembolization is widely used as palliative therapy for inoperable hepatocellalar carcinoma in high‐incidence Asiatic areas. To assess its usefulness in the Western form of this cancer, 20 French patients were treated between 1987 and 1990 by intraarterial hepatic injection of a Lipiodoldoxorubicin emulsion followed by embolization with 0.5 to 1 mm gelatin sponge particles. The number of procedures ranged from one to five.

Alexander L. Gerbes, Margit C. Kollenda, Angelika M. Vollmar, JÜRg Reichen, Nimish Vakil, Robert M. Scarborough – 1 March 1991 – The renal response to atrial natriuretic factor is blunted in cirrhosis with ascites. This might be due to alterations of renal receptors for atrial natriuretic factor. Therefore density and affinity of glomerular atrial natriuretic factor binding sites of bile duct–ligated rats with ascites (n = 10) and of sham‐operated controls (n = 10) were determined.

Yang‐Te Tsai, Fa‐Yauh Lee, Han‐Chieh Lin, Shou‐Dong Lee, Hsiao‐Chung Hsia, Wen‐Jeh Lin, Sun‐Sang Wang, Chii‐Shyan Lay, Kwok‐Hung Lai, Kwang‐Juei Lo – 1 March 1991 – It has been suggested that vasopressin given during hemorrhage may be less effective than when given during a stable state in a portal‐hypertensive rat model. This study was designed to evaluate the hemodynamic response to vasopressin infusion in 25 HBsAgpositive cirrhotic patients.