Ulrich Beuers, Ulrich Spengler, Franz M. Zwiebel, Juergen Pauletzki, Sven Fischer, Gustav Paumgartner – 1 April 1992 – Beneficial effects of ursodeoxycholic acid in chronic cholestatic liver diseases have been attributed to displacement of hydrophobic bile acids from the endogenous bile acid pool.
Claudia Martins Da Costa, Dianne Baldwin, Bernard Portmann, Yvette Lolin, Alex P. Mowat, Giorgina Mieli‐Vergani – 1 April 1992 – To investigate the diagnostic value of 24‐hr urinarycopper excretion testing after penicillamine challenge in the diagnosis of Wilson's disease, 75 consecutive children referred for a variety of liver problems and in whom parameters of copper metabolism had been investigated were analyzed retrospectively.
Giovanna Fattovich, Patrizia Farci, Massimo Rugge, Lucio Brollo, Antonella Mandas, Patrizia Pontisso, Giuliano Giustina, M. Eliana Lai, Fabio Belussi, Graziella Busatto, Angelo Balestrieri, Arturo Ruol, Alfredo Alberti – 1 April 1992 – Ongoing hepatitis B virus replication in the presence of antibody to HBeAg can be observed in patients with active liver disease. These forms of chronic hepatitis B have been described as having a poor prognosis.
James B. Burgess, Jacques U. Baenziger, William R. Brown – 1 April 1992 – Serum concentrations of asialoglycoproteins are increased in cirrhosis. We hypothesized that this increase results from abnormalities in the asialoglycoprotein receptor, which is located on the sinusoidal and lateral membrane of hepatocytes. Therefore we searched for morphological alterations in the distribution of the asialoglycoprotein receptor in human liver, using a light microscopic immunoperoxidase method in autopsy livers.
Robertson D. Davenport – 1 April 1992 – Prophylactic transfusions of fresh frozen plasma and platelets are sometimes given to patients with mild elevations in prothrombin time (PT) and partial thromboplastin time (PTF) and mild thrombocytopenia before percutaneous liver biopsy. To determine whether PTs and PTFs 1.1–1.5 times midrange normal levels and platelet counts 50–99 × 109/L are associated with increased bleeding complications, hospital records of all patients who underwent percutaneous liver biopsy during 56 consecutive months (n = 291) were reviewed.
Mario Chojkier, Kenji Fujiwara, Itsuro Ogata – 1 April 1992
Christopher Liddle, Michael Hollands, J. Miles Little, Geoffrey C. Farrell – 1 April 1992 – In both rats and humans, partial hepatectomy results in a substantial increase in serum estradiol concentrations. Because mammalian liver of both sexes contains estrogen receptor, it has been suggested that this surge in serum estrogen concentration may initiate or facilitate liver regeneration.
Manal Shahin, Detlef Schuppan, Rüdiger Waldherr, Juha Risteli, Leila Risteli, Eeva‐Riitta Savolainen, Christine Oesterling, Hosna M. Abdel Rahman, Abdul M. El Sahly, Samia M. Abdel Razek, Omar El Ruby, Armin Koch, Helmut K. Seitz – 1 April 1992 – Schistosomiasis, in contrast to alcoholic liver disease, leads to presinusoidal hepatic fibrosis, which determines the prognosis of the disease.