Michael Neubrand, Joseph Holl, Michael Sackmann, Ulrich Klüppelberg, Jürgen Pauletzki, Gustav Paumgartner, Tilman Sauerbruch – 1 January 1994 – We conducted a prospective randomized study in gallstone patients to determine whether a combination of extracorporeal shock‐wave lithotripsy and subsequent dissolution with methyl tert‐butyl ether increases the success rate of methyl tert‐butyl ether dissolution and shortens treatment time compared with monotherapy with methyl tert‐butyl ether. Fifty patients were randomized into two groups.

Judy A. Spitzer – 1 January 1994 – Some disease processes in which increased endotoxin and cytokine levels exist (e.g., sepsis and infantile diarrhea) are also associated with increased levels of blood nitrates, the stable and products of nitric oxide. Available evidence suggests that the effects of an endotoxic environment, with its attendant complex cytokine networks, on liver function are mediated in part by modulation of hepatic nitric oxide synthesis.

Robert G. Lamb, John C. Koch, Jack W. Snyder, Shiva M. Huband, Suzanne R. Bush – 1 January 1994 – Primary cultures of adult rat hepatocytes were incubated (6 to 96 hr) with 50 to 150 mmol/L ethanol, 0.5 mmol/L linoleate, 0.5 mmol/L palmitate, 0.5 mmol/L 4‐methylpyrazole, 0 to 25 μmol/L vitamin E phosphate or selected combinations of these agents.

Jeffrey D. Rothstein – 1 January 1994

Giulio Diodati, Paola Bonetti, Franco Noventa, Carla Casarin, Massimo Rugge, Sergio Scaccabarozzi, Alessandro Tagger, Lucio Pollice, Federico Tremolada, Cristina Davite, Giuseppe Realdi, Arturo Ruol – 1 January 1994 – Sixty consecutive patients with chronic hepatitis C were included in a randomized controlled trial of recombinant human interferon‐α2a vs. no treatment. Treated patients received tapering doses of interferon thrice weekly for 1 yr.

Koteswara R. Chintalacharuvu, Anthony S. Tavill, Loizos N. Louis, Jean‐Pierre Vaerman, Michael E. Lamm, Charlotte S. Kaetzel – 1 January 1994 – The polymeric immunoglobulin receptor on rat hepatocytes binds dimeric IgA on the sinusoidal surface and mediates its transport to the canaliculus, where the complex of dimeric IgA and secretory component, the cleaved extracellular domain of polymeric immunoglobulin receptor, is secreted into bile.

Francis Schneider, Philippe Lutun, Karim Boudjema, Philippe Wolf, Jean‐Daniel Tempé – 1 January 1994 – Nitric oxide and atrial natriuretic peptides are the main activators of guanylyl cyclases, which transform ITP into cyclic GMP and thereby contribute to the decrease of vascular tone.

Anton Chekhov, Michael R. Lucey – 1 January 1994

1 January 1994

Geoffrey Dusheiko, Hemda Schmilovitz‐Weiss, David Brown, Fiona McOmish, Pong‐Lee Yap, Sheila Sherlock, Neil McIntyre, Peter Simmonds – 1 January 1994 – Because of the nucleotide sequence diversity of different isolates of hepatitis C virus, it has become important to clarify whether distinct genotypes of hepatitis C virus vary with respect to pathogenicity, infectivity, response to antiviral therapy and geographic clustering.