Motoko Sasaki, Naoko Kono, Yasuni Nakanuma – 1 January 1994 – We examined the expression of Lewis antigens, particularly Lewis Y, on the intrahepatic biliary epithelial cells in normal livers and various hepatobiliary diseases with immunohistochemical and immunoelectron microscopic methods. In normal livers, Lewis Y was consistently and generally negative in the bile ductules and small bile ducts, respectively.

Xin Xu, Andreas J. Schwab, Ford Barker Iii, Carl A. Goresky, K. Sandy Pang – 1 January 1994 – The hepatocellular entry of salicylamide sulfate conjugate, which binds to both red blood cells and albumin, was examined with the multiple‐indicator dilution technique in the perfused rat liver, with medium containing both 20 red cells and 1 albumin (set A), red cells only (set B), albumin only (set C) and neither red cells nor albumin (set D).

Hubert E. Blum – 1 January 1994 – Background and Methods. To detect potentially curable cases of hepatocellular carcinoma, outpatients with chronic hepatitis or compensated liver cirrhosis who were seen at the Center for Adult Diseases (Osaka, Japan) were examined periodically by means of ultrasonography and measurement of serum alpha‐fetoprotein. Risk factors for hepatocellular carcinoma were identified with a Cox proportional‐hazards model.

Raymond S. Koff – 1 January 1994

Patricia K. Eagon, Mary S. Elm, Elizabeth A. Stafford, Lynne E. Porter – 1 January 1994 – Liver is responsive to sex hormones. The role of androgens in normal human liver function is not well understood, although androgens have been implicated in several liver diseases. Because the human hepatic androgen receptor has not been adequately characterized, we analyzed cytosolic and nuclear fractions from normal human liver of both sexes for androgenbinding activity using multipoint saturation analysis with the androgenic radioligand methyltrienelone (R1881).

Shigetoshi Okumura, Yoshiyuki Takei, Sunao Kawano, Kouichi Nagano, Eiji Masuda, Moritaka Goto, Shingo Tsuji, Tomoki Michida, Sheng‐Song Chen, Toru Kashiwagi, Hideyuki Fusamoto, Takenobu Kamada, Nobuhiro Sato – 1 January 1994 – The purpose of this study was to evaluate the role of endothelin‐1 in modulating hepatic microcirculation and liver damage. Rats were infused with endothelin‐1 at doses ranging from 30 to 1,000 pmol/kg over 1 min through an indwelling cannula placed in the portal vein. In control rats, saline solution was infused at the same rate.

Andrea Ewing Reid, T. Jake Liang – 1 January 1994

Karl T. Benedict – 1 January 1994

Yves M. Deugnier, Paul Charalambous, Daniéle Le Quilleuc, Bruno Turlin, Jeffrey Searle, Pierre Brissot, Lawrie W. Powell, June W. Halliday – 1 December 1993 – Sublobular nodules of hepatocytes free of iron or exhibiting much less iron than the surrounding parenchyma, referred to in this study as iron‐free‐foci, are frequently found in the livers of patients with genetic hemochromatosis complicated by hepatocellular carcinoma.

Vijayan Balan, Kennetii P. Batts, Michael K. Porayko, Ruud A. F. Krom, Jurgen Ludwig, Russell H. Wiesner – 1 December 1993 – Whether primary biliary cirrhosis recurs after orthotopic liver transplantation remains a controversial issue. Sixty consecutive patients with primary biliary cirrhosis with at least 1 yr of follow‐up after liver transplantation were studied. All patients were treated with triple‐drug immunosuppression (cyclospoine, prednisone, azathioprine).