Prediction of Alcohol Relapse Among Liver Transplant Candidates With Less Than 6 Months of Abstinence Using the High‐Risk Alcoholism Relapse Score

Julissa Lombardo‐Quezada, Jordi Colmenero, Hugo López‐Pelayo, Carolina Gavotti, Ana Lopez, Gonzalo Crespo, Eva Lopez, Antoni Gual, Anna Lligoña, Miquel Navasa – 28 March 2019 – The selection of liver transplantation (LT) candidates with alcohol‐use disorder (AUD) is influenced by the risk of alcohol relapse (AR) after LT. We aimed to investigate the risk factors of AR after LT and its impact on graft and recipient outcomes.

Looking Into the Crystal Ball: Predicting the Future Challenges of Fibrotic NASH Treatment

Naim Alkhouri, Eric Lawitz, Mazen Noureddin – 28 March 2019 – Nonalcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease worldwide, and its aggressive form of nonalcoholic steatohepatitis (NASH) is becoming a leading cause for end‐stage liver disease and liver transplantation in the United States. In patients with NASH, the presence of advanced fibrosis is considered the most important prognostic factor in predicting liver‐related morbidity and mortality.

Expanding and Underscoring the Hepato‐Encephalopathic Phenotype of QIL1/MIC13

Bianca E. Russell, Kaitlin G. Whaley, Kevin E. Bove, Anatalia Labilloy, Rachel C. Lombardo, Robert J. Hopkin, Nancy D. Leslie, Carlos Prada, Zahra Assouline, Giulia Barcia, Juliette Bouchereau, Maryline Chomton, Dominique Debray, Imen Dorboz, Philippe Durand, Pauline Gaignard, Dalila Habes, Claude Jardel, François Labarthe, Jonathan Lévy, Anne Lombès, Claire Mehler‐Jacob, Judith Melki, Laura Menvielle, Arnold Munnich, Charlotte Mussini, Samia Pichard, Marlène Rio, Agnès Rötig, Samira Sissaoui, Abdelhamid Slama, Alexander G Miethke, Manuel Schiff – 26 March 2019

The Effects of Liver Transplantation in Children With Niemann‐Pick Disease Type B

Yuan Liu, Yi Luo, Lei Xia, Bijun Qiu, Tao Zhou, Mingxuan Feng, Feng Xue, Xiaosong Chen, Longzhi Han, Jianjun Zhang, Qiang Xia – 26 March 2019 – We evaluated the effects of liver transplantation (LT) in children with Niemann‐Pick disease (NPD) type B. From October 2006 to October 2018, 7 of 1512 children who received LT at Ren Ji Hospital were diagnosed as NPD type B. The median age at diagnosis was 12 months (6‐14 months) with initial presentations of hepatosplenomegaly, growth retardation, repeated pneumonia, and diarrhea.

Clinical Implications of Donor Warm and Cold Ischemia Time in Donor After Circulatory Death Liver Transplantation

Flavio Paterno, James V. Guarrera, Koffi Wima, Tayyab Diwan, Madison C. Cuffy, Nadeem Anwar, E. Steve Woodle, Shimul Shah – 26 March 2019 – The use of donation after circulatory death (DCD) liver allografts has been constrained by limitations in the duration of donor warm ischemia time (DWIT), donor agonal time (DAT), and cold ischemia time (CIT). The purpose of this study is to assess the impact of longer DWIT, DAT, and CIT on graft survival and other outcomes in DCD liver transplants.

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