Martine C. Morrison, Lars Verschuren, Kanita Salic, Joanne Verheij, Aswin Menke, Peter Y. Wielinga, Marta Iruarrizaga‐Lejarreta, Laurent Gole, Wei‐Miao Yu, Scott Turner, Martien P.M. Caspers, Ibon Martínez‐Arranz, Elsbet Pieterman, Reinout Stoop, Arianne van Koppen, Anita M. van den Hoek, José M.
David Tornai, Istvan Furi, Zu T. Shen, Alexander B. Sigalov, Sahin Coban, Gyongyi Szabo – 29 October 2018 – Alcoholic liver disease (ALD) is characterized by macrophage and neutrophil leukocyte recruitment and activation in the liver. Damage‐ and pathogen‐associated molecular patterns contribute to a self‐perpetuating proinflammatory state in ALD. Triggering receptor expressed on myeloid cells 1 (TREM‐1) is a surface receptor that amplifies inflammation induced by toll‐like receptors (TLRs) and is expressed on neutrophils and monocytes/macrophages.
Geoff Farrell, Jörn M. Schattenberg, Isabelle Leclercq, Matthew M. Yeh, Robert Goldin, Narci Teoh, Detlef Schuppan – 29 October 2018 – Nonalcoholic steatohepatitis (NASH) arises from a variable interplay between environmental factors and genetic determinants that cannot be completely replicated in animals. Notwithstanding, preclinical models are needed to understand NASH pathophysiology and test mechanism‐based therapies.
Cristiano Quintini, Laura Lomaglio, Daniele Pezzati, Teresa Diago Uso, Qiang Liu – 29 October 2018
Martine C. Morrison, Lars Verschuren, Kanita Salic, Joanne Verheij, Aswin Menke, Peter Y. Wielinga, Marta Iruarrizaga‐Lejarreta, Laurent Gole, Wei‐Miao Yu, Scott Turner, Martien P.M. Caspers, Ibon Martínez‐Arranz, Elsbet Pieterman, Reinout Stoop, Arianne van Koppen, Anita M. van den Hoek, José M.
Toshimasa Nakao, Yoshihiro Ono, Helong Dai, Ryosuke Nakano, Angelica Perez‐Gutierrez, Geoffrey Camirand, Hai Huang, David A. Geller, Angus W. Thomson – 29 October 2018 – Liver interstitial dendritic cells (DCs) have been implicated in the control of ischemia–reperfusion injury (IRI) and host immune responses following liver transplantation. Mechanisms underlying these regulatory functions of hepatic DCs remain unclear.
Aysha Aslam, Rizwan Ishtiaq, Dary T.Y. Lau – 29 October 2018
Graciela Elia Castro Narro, Armando Gamboa Domínguez, Alejandra Consuelo Sánchez, Abel Salazar Martínez, Jose Agramonte Hevia, J.J. Cebolla, Miguel Enrique Cuellar Mendoza, Héctor Adrián Díaz Hernández – 29 October 2018
Rajab Idriss, Jeanette Hasse, Tiffany Wu, Fatima Khan, Giovanna Saracino, Greg McKenna, Giuliano Testa, James Trotter, Goran Klintmalm, Sumeet K. Asrani – 28 October 2018 – Bariatric surgery (BS) is effective in treating morbid obesity, but the impact of prior BS on candidacy for liver transplantation (LT) is unclear. We examined 78 patients with cirrhosis with prior BS compared with a concurrent cohort of 156 patients matched by age, Model for End‐Stage Liver Disease score, and underlying liver disease.
Miklos Z. Molnar, Kiran Joglekar, Yu Jiang, George Cholankeril, Mubeen Khan Mohammed Abdul, Satish Kedia, Humberto C. Gonzalez, Aijaz Ahmed, Ashwani Singal, Kalyan Ram Bhamidimarri, Guruprasad Padur Aithal, Ajay Duseja, Vincent Wai‐Sun Wong, Agayeva Gulnare, Puneet Puri, Satheesh Nair, James D. Eason, Sanjaya K. Satapathy, the Global NAFLD Consortium – 28 October 2018 – Nonalcoholic steatohepatitis (NASH) is one of the top 3 indications for liver transplantation (LT) in Western countries.