Posttranscriptional Inhibition of Protein Tyrosine Phosphatase Nonreceptor Type 23 by Staphylococcal Nuclease and Tudor Domain Containing 1: Implications for Hepatocellular Carcinoma

Nidhi Jariwala, Rachel G. Mendoza, Dawn Garcia, Zhao Lai, Mark A. Subler, Jolene J. Windle, Nitai D. Mukhopadhyay, Paul B. Fisher, Yidong Chen, Devanand Sarkar – 15 July 2019 – Oncoprotein staphylococcal nuclease and tudor domain containing 1 (SND1) regulates gene expression at a posttranscriptional level in multiple cancers, including hepatocellular carcinoma (HCC). Staphylococcal nuclease (SN) domains of SND1 function as a ribonuclease (RNase), and the tudor domain facilitates protein–oligonucleotide interaction.

Twitter As a Noninvasive Bio‐Marker for Trends in Liver Disease

Ben L. Da, Pallavi Surana, Samuel A. Schueler, Niloofar Y. Jalaly, Natasha Kamal, Sonia Taneja, Anusha Vittal, Christy L. Gilman, Theo Heller, Christopher Koh – 13 July 2019 – With the success of hepatitis C virus (HCV) direct‐acting antiviral therapies, there has been a shift in research focus to the other major chronic liver diseases (CLDs). The use of social media, specifically Twitter, has become a popular platform for understanding public health trends and for performing health care research.

Diagnosis, Outcome, and Management of Chylous Ascites Following Pediatric Liver Transplantation

Mar Miserachs, Eberhard Lurz, Aviva Levman, Anand Ghanekar, Mark Cattral, Vicky Ng, David Grant, Yaron Avitzur – 13 July 2019 – Data on postoperative chylous ascites (CA) after pediatric liver transplantation (LT) are scarce. This retrospective study was conducted to identify the incidence, risk factors, management, and outcomes of postoperative CA in a large single‐center pediatric LT cohort (2000‐2016). The study cohort comprised 317 LTs (153 living donors and 164 deceased donors) in 310 recipients with a median age of 2.7 years.

Nutritional Assessment in Inpatients With Cirrhosis Can Be Improved After Training and Is Associated With Lower Readmissions

Bradley Reuter, Jawaid Shaw, Jennifer Hanson, Victoria Tate, Chathur Acharya, Jasmohan S. Bajaj – 13 July 2019 – Malnutrition is widely prevalent in cirrhosis patients, which can worsen sarcopenia, hepatic encephalopathy (HE), and overall prognosis. We aimed to define the frequency of nutritional assessments of patients with cirrhosis in retrospective and prospective (after educational training) cohorts and to evaluate prospective changes along with their effects on 90‐day readmissions. This study was conducted in 2 phases.

Subscribe to