Katherine H. Ross, Rachel E. Patzer, David Goldberg, Nicolas H. Osborne, Raymond J. Lynch – 17 June 2019 – Access to quality hospital care is a persistent problem for rural patients. Little is known about disparities between rural and urban populations regarding in‐hospital outcomes for end‐stage liver disease (ESLD) patients. We aimed to determine whether rural ESLD patients experienced higher in‐hospital mortality than urban patients and whether disparities were attributable to the rurality of the patient or the center.

Benjamin Y. Winer, Jenna M. Gaska, Gabriel Lipkowitz, Yaron Bram, Amit Parekh, Lance Parsons, Robert Leach, Rohit Jindal, Cheul H. Cho, Anil Shrirao, Eric Novik, Robert E. Schwartz, Alexander Ploss – 17 June 2019 – Hepatitis B virus (HBV) remains a major global health problem with 257 million chronically infected individuals worldwide, of whom approximately 20 million are co‐infected with hepatitis delta virus (HDV).

Naoto Fujiwara, Amit G. Singal, Yujin Hoshida – 17 June 2019

Salvatore Lorenzo Renne, Ha Young Woo, Sarah Allegra, Noemi Rudini, Hirohisa Yano, Matteo Donadon, Luca Viganò, Jun Akiba, Hye Sun Lee, Hyungjin Rhee, Young Nyun Park, Massimo Roncalli, Luca Di Tommaso – 17 June 2019 – We investigated the clinical significance of a vascular growth pattern of hepatocellular carcinoma (HCC), the vessels that encapsulate tumor clusters (VETC), previously linked to HCC metastatic dissemination.

Justin D. Schumacher, Bo Kong, Jason Wu, Daniel Rizzolo, Laura E. Armstrong, Monica D. Chow, Michael Goedken, Yi‐Horng Lee, Grace L. Guo – 17 June 2019 – Farnesoid X receptor (FXR) induces fibroblast growth factor 15 (FGF15; human ortholog FGF19) in the gut to potently inhibit bile acid (BA) synthesis in the liver. FXR activation in hepatic stellate cells (HSCs) reduces liver fibrosis (LF). Fgf15–/– mice develop attenuated LF, but the underlying mechanisms for this protection are unclear.

Anne J. Klompenhouwer, Maarten G.J. Thomeer, Winand N.M. Dinjens, Robert A. Man, Jan N.M. Ijzermans, Michail Doukas – 17 June 2019

Carlo D. L. Ceresa, David Nasralla, Christopher J. E. Watson, Andrew J. Butler, Constantin C. Coussios, Keziah Crick, Leanne Hodson, Charles Imber, Wayel Jassem, Simon R. Knight, Hynek Mergental, Rutger J. Ploeg, Joerg M. Pollok, Alberto Quaglia, A. M. James Shapiro, Annemarie Weissenbacher, Peter J. Friend – 17 June 2019 – Clinical adoption of normothermic machine perfusion (NMP) may be facilitated by simplifying logistics and reducing costs. This can be achieved by cold storage of livers for transportation to recipient centers before commencing NMP.

Seth Karp – 17 June 2019

** VIEW ONLY CONTENT . The Clinical Hepatology Update 2019 enduring course will be available soon. It will be available under the "On-Demand Accredited Activities". ** The Clinical Hepatology Update conference is designed for all medical professionals who manage care for patients with liver disease, including nurse practitioners, physician assistants, RNs, primary care physicians, medical students and GI or hepatology trainees. The conference will provide an update and review of the evolving practices in the clinical management of liver diseases.

Kristopher P. Croome, David D. Lee, Sarah Croome, Raouf E. Nakhleh, Peter Abader Sedki Senada, David Livingston, Maria Yataco, C. Burcin Taner – 12 June 2019 – It has been suggested that microsteatosis does not negatively impact graft survival following liver transplantation (LT). The present study represents the largest series on donor livers with significant microsteatosis and investigates the impact of microsteatosis on perioperative factors such as postreperfusion syndrome (PRS), early allograft dysfunction (EAD), and postoperative renal dysfunction.