Molecular Mechanism for Protection Against Liver Failure in Human Yellow Fever Infection

Fernanda de Oliveira Lemos, Andressa França, Antônio Carlos Melo Lima Filho, Rodrigo M. Florentino, Marcone Loiola Santos, Dabny G. Missiaggia, Gisele Olinto Libanio Rodrigues, Felipe Ferraz Dias, Ingredy Beatriz Souza Passos, Mauro M. Teixeira, Antônio Márcio de Faria Andrade, Cristiano Xavier Lima, Paula Vieira Teixeira Vidigal, Vivian Vasconcelos Costa, Matheus Castro Fonseca, Michael H. Nathanson, M. Fatima Leite – 16 March 2020 – Yellow fever (YF) is a viral hemorrhagic fever that typically involves the liver.

Lysyl Oxidase (LOX) Family Members: Rationale and Their Potential as Therapeutic Targets for Liver Fibrosis

Wei Chen, Aiting Yang, Jidong Jia, Yury V. Popov, Detlef Schuppan, Hong You – 16 March 2020 – The cross‐linking of structural extracellular matrix (ECM) components, especially fibrillar collagens and elastin, is strongly implicated in fibrosis progression and resistance to fibrosis reversal.

Lysyl Oxidase (LOX) Family Members: Rationale and Their Potential as Therapeutic Targets for Liver Fibrosis

Wei Chen, Aiting Yang, Jidong Jia, Yury V. Popov, Detlef Schuppan, Hong You – 16 March 2020 – The cross‐linking of structural extracellular matrix (ECM) components, especially fibrillar collagens and elastin, is strongly implicated in fibrosis progression and resistance to fibrosis reversal.

Integrated GWAS and mRNA Microarray Analysis Identified IFNG and CD40L as the Central Upstream Regulators in Primary Biliary Cholangitis

Kazuko Ueno, Yoshihiro Aiba, Yuki Hitomi, Shinji Shimoda, Hitomi Nakamura, Olivier Gervais, Yosuke Kawai, Minae Kawashima, Nao Nishida, Seik‐Soon Kohn, Kaname Kojima, Shinji Katsushima, Atsushi Naganuma, Kazuhiro Sugi, Tatsuji Komatsu, Tomohiko Mannami, Kouki Matsushita, Kaname Yoshizawa, Fujio Makita, Toshiki Nikami, Hideo Nishimura, Hiroshi Kouno, Hirotaka Kouno, Hajime Ohta, Takuya Komura, Satoru Tsuruta, Kazuhiko Yamauchi, Tatsuro Kobata, Amane Kitasato, Tamotsu Kuroki, Seigo Abiru, Shinya Nagaoka, Atsumasa Komori, Hiroshi Yatsuhashi, Kiyoshi Migita, Hiromasa Ohira, Atsushi Tanaka, Haji

Liver injury during highly pathogenic human coronavirus infections

Ling Xu, Jia Liu, Mengji Lu, Dongliang Yang, Xin Zheng – 14 March 2020 – The severe acute respiratory syndrome coronavirus 2 (SARS‐Cov‐2), the pathogen of 2019 novel coronavirus disease (COVID‐19), has posed a serious threat to global public health. The WHO has declared the outbreak of SARS‐CoV‐2 infection an international public health emergency. Lung lesions have been considered as the major damage caused by SARS‐CoV‐2 infection. However, liver injury has also been reported to occur during the course of the disease in severe cases.

Hepatitis B Virus–Telomerase Reverse Transcriptase Promoter Integration Harnesses Host ELF4, Resulting in Telomerase Reverse Transcriptase Gene Transcription in Hepatocellular Carcinoma

Karen Man‐Fong Sze, Daniel Wai‐Hung Ho, Yung‐Tuen Chiu, Yu‐Man Tsui, Lo‐Kong Chan, Joyce Man‐Fong Lee, Kenneth Siu‐Ho Chok, Albert Chi‐Yan Chan, Chung‐Ngai Tang, Victor Wai‐Lun Tang, Irene Lai‐Oi Lo, Derek Tsz‐Wai Yau, Tan‐To Cheung, Irene Oi‐Lin Ng – 14 March 2020

Annexin A6 Is Critical to Maintain Glucose Homeostasis and Survival During Liver Regeneration in Mice

Anna Alvarez‐Guaita, Patricia Blanco‐Muñoz, Elsa Meneses‐Salas, Mohamed Wahba, Abigail H. Pollock, Jaimy Jose, Mercedes Casado, Marta Bosch, Rafael Artuch, Katharina Gaus, Albert Lu, Albert Pol, Francesc Tebar, Stephen E. Moss, Thomas Grewal, Carlos Enrich, Carles Rentero – 14 March 2020

Subscribe to