Interaction between hepatitis B surface proteins and monomeric human serum albumin
Bernd Krone, Angela Lenz, Klaus‐Hinrich Heermann, Maria Seifer, Lu Xuangyong, Wolfram H. Gerlich – 1 June 1990 – HBsAg is known to bind to human serum albumin polymerized by glutaraldehyde, human serum albumin has been found in preparations of HBsAg by several investigators. However, it is not yet known whether natural human serum albumin binds to hepatitis B virus under physiological conditions. We studied the binding between natural or recombinant HBsAg and monomeric human serum albumin by immunological, biochemical and biophysical methods.