Hepatocyte growth factor induces proliferation and morphogenesis in nonparenchymal epithelial liver cells
Mark Johnson, George Koukoulis, Kunio Matsumoto, Toshikazu Nakamura, Anand Iyer – 1 June 1993 – Hepatocyte growth factor is the most potent mitogen known for hepatocytes, and increasing evidence suggests that hepatocyte growth factor plays an important role in liver regeneration. However, hepatocytes are not the only liver epithelial cell population that proliferates during regeneration. Experimental and clinical data indicate that the regenerative liver response also includes the participation of nonparenchymal epithelial cells.