Roberto J. Groszmann – 1 November 1994

Walter H. Abelmann – 1 November 1994

Kathryn A. Quinn, Alice C. Cavanagh, Narelle C. Hillyard, Dorothy A. McKay, Halle Morton – 1 November 1994 – Early pregnancy factor is not only a product of dividing embryonic and neoplastic cells, as demonstrated previously, but also of normal proliferating cells. Eight hours after partial hepatectomy in rats, early pregnancy factor was detected in serum. It rose to a peak by 48 hr.

Simon D. Taylor‐Robinson, Janet Sargentoni, Rosemary J. Mallalieu, Jimmy D. Bell, David J. Bryant, Glyn A. Coutts, Marsha Y. Morgan – 1 November 1994 – Cerebral phosphorus‐31 magnetic resonance spectroscopy was undertaken in 33 patients with biopsyproven cirrhosis: 6 had no evidence of neuropsychiatric impairment on standard clinical, psychometric and electrophysiological testing; 8 had evidence of subclinical hepatic encephalopathy; and 19 were classified as having overt hepatic encephalopathy. The reference population comprised 15 healthy volunteers.

Cyrille Féray, Michelle Gigou, Didier Samuel, Valérie Paradis, Judith Wilber, Marie France David, Mickey Urdea, Michel Reynes, Christian Bréchot, Henri Bismuth – 1 November 1994 – Hepatitis C virus—induced liver disease is becoming a main indication for liver transplantation. Recurrence of hepatitis after transplantation has been reported, but its long‐term consequences are unknown.

Masahide Oshita, Yoshiyuki Takei, Sunao Kawano, Taizo Hijioka, Eiji Masuda, Moritaka Goto, Yoshiya Nishimura, Hirotaka Nagai, Sadaharu Iio, Shingo Tsuji, Hideyuki Fusamoto, Takenobu Kamada – 1 October 1994 – The purpose of this study was to clarify the role of endogenous nitric oxide in ethanol‐induced perturbation of microcirculation and hepatic injury in perfused rat liver. Infusion of ethanol into the portal vein at 25 and 100 mmol/L increased portal pressure, which is an indicator of hepatic vasoconstriction, in a concentration‐dependent fashion.

Makoto Hoshino, Tomihiro Hayakawa, Asamitsu Hirano, Yasutaka Kamiya, Takayuki Ohiwa, Akitaka Tanaka, Tomoyuki Kumai, Takanori Inagaki, Makoto Miyaji, Toshihiko Takeuchi – 1 October 1994 – We investigated bile flow and biliary excretion of bile acids in the Eisai hyperbilirubinemic rat, a Sprague‐Dawley mutant rat with conjugated hyperbilirubinemia, using both in vivo and in vitro models. In vivo bile flow was lower in Eisai hyperbilirubinemic rats than in the control rats before and after taurocholate was infused.

Florence Wong, Denise Massie, Paul Hsu, Francis Dudley – 1 October 1994 – A total of 29 patients with well‐compensated alcoholic cirrhosis and 9 healthy control subjects of similar age and sex were studied to assess their response to a challenge of 2 L of normal saline infused over a 1 hr period. Patients with cirrhosis had an adequate effective arterial blood volume in the basal state as assessed by neurohumoral markers of vascular filling.

1 October 1994

Albert D. Min – 1 October 1994