Joan Clària, Wladimiro Jiménez Ph.D., Josefa Ros, Montserrat Rigol, Paolo Angeli, Vicente Arroyo, Francisca Rivera, Joan Rodés – 1 December 1994 – To assess whether aortic vessels of rats with cirrhosis and ascites possess an enhanced vascular response to endothelium‐derived, nitric oxide—dependent vasodilators, we performed relaxation studies in isolated aortic rings of 21 control rats and 24 rats with carbon tetrachloride—induced cirrhosis and ascites. We carried out studies after contracting the vessels with norepinephrine.

Andrea E. Reid, T. Jake Liang – 1 December 1994

Christian Madl, Georg Grimm, Peter Ferenci, Ludwig Kramer, Wafa Yeganehfar, Walter Oder, Rudolf Steininger, Christian Zauner, Klaus Ratheiser, Felix Stockenhuber, Kurt Lenz – 1 December 1994 – Sensory evoked potentials are markedly changed in patients with fulminant liver failure. It is unknown, however, whether serial recordings of sensory evoked potentials provide useful prognostic informations for patient management in fulminant liver failure.

Cyrille Féray, Michelle Gigou, Didier Samuel, Valérie Paradis, Judith Wilber, Marie France David, Mickey Urdea, Michel Reynes, Christian Bréchot, Henri Bismuth – 1 November 1994 – Hepatitis C virus—induced liver disease is becoming a main indication for liver transplantation. Recurrence of hepatitis after transplantation has been reported, but its long‐term consequences are unknown.

Simon D. Taylor‐Robinson, Janet Sargentoni, Rosemary J. Mallalieu, Jimmy D. Bell, David J. Bryant, Glyn A. Coutts, Marsha Y. Morgan – 1 November 1994 – Cerebral phosphorus‐31 magnetic resonance spectroscopy was undertaken in 33 patients with biopsyproven cirrhosis: 6 had no evidence of neuropsychiatric impairment on standard clinical, psychometric and electrophysiological testing; 8 had evidence of subclinical hepatic encephalopathy; and 19 were classified as having overt hepatic encephalopathy. The reference population comprised 15 healthy volunteers.

Kathryn A. Quinn, Alice C. Cavanagh, Narelle C. Hillyard, Dorothy A. McKay, Halle Morton – 1 November 1994 – Early pregnancy factor is not only a product of dividing embryonic and neoplastic cells, as demonstrated previously, but also of normal proliferating cells. Eight hours after partial hepatectomy in rats, early pregnancy factor was detected in serum. It rose to a peak by 48 hr.

Walter H. Abelmann – 1 November 1994

Roberto J. Groszmann – 1 November 1994

Mark E. Peeples – 1 November 1994 – In a previous study, we have identified endonexin II (E‐II) on human liver plasma membranes as a specific, Ca‐dependent, small hepatitis B surface antigen (HBsAg)‐binding protein. In this article, we describe the spontaneous development of anti‐HBs antibodies in rabbits immunized with native or recombinant human liver E‐II and in chickens immunized with the F(ab′)2 fragment of rabbit anti‐human liver E‐II immunoglobulin G. Anti‐HBs activity was not observed in rabbits immunized with rat liver E‐II.

Iljia Toshkov, Francis V. Chisari, Peter Bannasch – 1 November 1994 – Hepatocarcinogenesis in hepatitis B virus transgenic mice was studied by means of a correlative cytomorphological and cytochemical approach at different time points in animals from 1 to 34 mo old. HBsAg‐positive ground‐glass hepatocytes emerged throughout the liver parenchyma in nearly all transgenic mice during the first 4 mo after birth. The panlobular expression of HBsAg persisted until foci of altered hepatocytes appeared (6 to 9 mo of age).